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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDS5B All Species: 19.39
Human Site: S1311 Identified Species: 35.56
UniProt: Q9NTI5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTI5 NP_055847.1 1447 164667 S1311 E E P T M K T S K K G S K K K
Chimpanzee Pan troglodytes XP_509623 1487 169149 S1351 E E P T M K T S K K G S K K K
Rhesus Macaque Macaca mulatta XP_001118201 1528 173307 S1391 E E P T L K T S K K G S K K K
Dog Lupus familis XP_543139 1623 183240 K1487 E P T M K T S K K G A K K K S
Cat Felis silvestris
Mouse Mus musculus Q4VA53 1446 164401 S1309 E E P T M K T S K K G N K K K
Rat Rattus norvegicus Q6TRW4 1447 164441 S1310 E E P V V K T S K K G N K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509617 1452 165101 R1314 K A S K R G S R K R S G P P A
Chicken Gallus gallus Q5F3U9 1412 161007 E1274 R L K E D V I E S E D E Q N S
Frog Xenopus laevis Q5U241 1464 166906 G1314 P V T T P K R G R K N V V P I
Zebra Danio Brachydanio rerio A1L1F4 1320 148940 S1185 T N K S R D V S S E V G A R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610719 1218 138870 L1083 I K H R E F S L G S D K R D N
Honey Bee Apis mellifera XP_623860 1203 137941 N1068 K P E D N N M N Y K L W A V C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790621 1624 181368 A1384 K S A T P K S A T P T T T T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 94.3 88.4 N.A. 96.3 96.4 N.A. 94.4 91.4 84.4 63.9 N.A. 27.9 33.6 N.A. 40.3
Protein Similarity: 100 97.1 94.5 88.8 N.A. 97.7 97.7 N.A. 96.6 94.6 90.4 75.4 N.A. 46.5 52.3 N.A. 58.8
P-Site Identity: 100 100 93.3 26.6 N.A. 93.3 80 N.A. 6.6 0 20 6.6 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 33.3 N.A. 100 93.3 N.A. 26.6 13.3 26.6 33.3 N.A. 20 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 8 0 0 8 0 16 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 8 8 0 0 0 0 16 0 0 8 0 % D
% Glu: 47 39 8 8 8 0 0 8 0 16 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 8 8 8 39 16 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 24 8 16 8 8 54 0 8 54 54 0 16 47 47 39 % K
% Leu: 0 8 0 0 8 0 0 8 0 0 8 0 0 0 0 % L
% Met: 0 0 0 8 24 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 8 0 8 0 0 8 16 0 8 8 % N
% Pro: 8 16 39 0 16 0 0 0 0 8 0 0 8 16 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 0 8 16 0 8 8 8 8 0 0 8 8 8 % R
% Ser: 0 8 8 8 0 0 31 47 16 8 8 24 0 0 16 % S
% Thr: 8 0 16 47 0 8 39 0 8 0 8 8 8 8 0 % T
% Val: 0 8 0 8 8 8 8 0 0 0 8 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _