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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDS5B
All Species:
36.36
Human Site:
Y354
Identified Species:
66.67
UniProt:
Q9NTI5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTI5
NP_055847.1
1447
164667
Y354
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Chimpanzee
Pan troglodytes
XP_509623
1487
169149
Y394
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Rhesus Macaque
Macaca mulatta
XP_001118201
1528
173307
Y434
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Dog
Lupus familis
XP_543139
1623
183240
Y529
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q4VA53
1446
164401
Y354
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Rat
Rattus norvegicus
Q6TRW4
1447
164441
Y354
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509617
1452
165101
Y354
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Chicken
Gallus gallus
Q5F3U9
1412
161007
Y354
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Frog
Xenopus laevis
Q5U241
1464
166906
Y354
L
A
K
D
L
T
E
Y
L
K
V
R
S
H
D
Zebra Danio
Brachydanio rerio
A1L1F4
1320
148940
F341
V
R
L
E
C
V
K
F
A
S
H
C
L
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610719
1218
138870
K239
V
M
D
K
P
N
T
K
L
S
I
T
N
K
I
Honey Bee
Apis mellifera
XP_623860
1203
137941
A225
T
L
E
P
Y
I
Q
A
F
F
N
H
V
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790621
1624
181368
R351
L
V
T
D
L
S
D
R
L
R
E
R
A
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.3
88.4
N.A.
96.3
96.4
N.A.
94.4
91.4
84.4
63.9
N.A.
27.9
33.6
N.A.
40.3
Protein Similarity:
100
97.1
94.5
88.8
N.A.
97.7
97.7
N.A.
96.6
94.6
90.4
75.4
N.A.
46.5
52.3
N.A.
58.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
0
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
33.3
N.A.
26.6
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
0
0
0
0
8
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
77
0
0
8
0
0
0
0
0
0
0
77
% D
% Glu:
0
0
8
8
0
0
70
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
77
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
16
% I
% Lys:
0
0
70
8
0
0
8
8
0
70
0
0
0
8
0
% K
% Leu:
77
8
8
0
77
0
0
0
85
0
0
0
8
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
8
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
8
0
77
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
16
0
0
70
0
0
% S
% Thr:
8
0
8
0
0
70
8
0
0
0
0
8
0
0
0
% T
% Val:
16
8
0
0
0
8
0
0
0
0
70
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _