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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
6.97
Human Site:
S28
Identified Species:
9.58
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
S28
P
S
P
D
G
A
S
S
D
A
E
P
E
P
P
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
S28
P
S
P
D
G
A
S
S
D
A
E
P
E
P
P
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
D28
S
P
D
G
A
S
S
D
T
E
P
E
P
P
S
Dog
Lupus familis
XP_535848
1288
147094
D28
S
P
D
G
P
S
S
D
A
E
P
E
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
D28
S
Q
D
G
A
H
S
D
E
E
M
E
Q
P
A
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
T28
I
G
P
F
Q
R
F
T
A
I
I
G
P
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
Chicken
Gallus gallus
NP_989849
1274
145838
T45
P
P
P
P
P
A
M
T
N
E
A
G
A
P
R
Frog
Xenopus laevis
P50532
1290
146971
P28
M
A
E
R
S
R
A
P
D
A
L
Q
A
D
P
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
P28
V
S
K
P
R
K
A
P
S
T
A
V
Q
S
S
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
E29
P
R
D
D
S
E
D
E
L
D
V
P
P
P
K
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
P43
I
R
S
N
I
P
T
P
A
T
S
G
T
G
I
Honey Bee
Apis mellifera
XP_396862
1282
148175
D28
E
E
G
G
I
R
I
D
D
D
I
Y
I
P
P
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
N36
K
K
T
T
K
P
V
N
R
H
K
E
G
S
K
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
Q47
E
K
K
T
L
A
L
Q
Q
A
K
N
T
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
E28
T
P
R
L
Y
I
K
E
L
V
M
R
N
F
K
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
G100
P
P
K
T
S
S
R
G
R
D
H
K
S
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
13.3
20
N.A.
13.3
6.6
N.A.
0
26.6
20
6.6
26.6
0
20
0
13.3
P-Site Similarity:
100
100
20
26.6
N.A.
26.6
13.3
N.A.
0
40
33.3
20
26.6
13.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
12
24
12
0
18
24
12
0
12
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
18
0
0
6
24
24
18
0
0
0
6
0
% D
% Glu:
12
6
6
0
0
6
0
12
6
24
12
24
12
0
0
% E
% Phe:
0
0
0
6
0
0
6
0
0
0
0
0
0
6
0
% F
% Gly:
0
6
6
24
12
0
0
6
0
0
0
18
6
6
6
% G
% His:
0
0
0
0
0
6
0
0
0
6
6
0
0
0
0
% H
% Ile:
12
0
0
0
12
6
6
0
0
6
12
0
6
6
6
% I
% Lys:
6
12
18
0
6
6
6
0
0
0
12
6
0
0
18
% K
% Leu:
0
0
0
6
6
0
6
0
12
0
6
0
0
0
0
% L
% Met:
6
0
0
0
0
0
6
0
0
0
12
0
0
0
6
% M
% Asn:
0
0
0
6
0
0
0
6
6
0
0
6
6
6
0
% N
% Pro:
30
30
24
12
12
12
0
18
0
0
12
18
24
48
30
% P
% Gln:
0
6
0
0
6
0
0
6
6
0
0
6
12
0
0
% Q
% Arg:
0
12
6
6
6
18
6
0
12
0
0
6
0
0
6
% R
% Ser:
18
18
6
0
18
18
30
12
6
0
6
0
6
12
18
% S
% Thr:
6
0
6
18
0
0
6
12
6
12
0
0
12
0
0
% T
% Val:
6
0
0
0
0
0
6
0
0
6
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
0
0
6
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _