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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
6.36
Human Site:
S36
Identified Species:
8.75
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
S36
D
A
E
P
E
P
P
S
G
R
T
E
S
P
A
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
S36
D
A
E
P
E
P
P
S
G
R
T
E
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
G36
T
E
P
E
P
P
S
G
R
A
E
S
P
A
T
Dog
Lupus familis
XP_535848
1288
147094
G36
A
E
P
E
P
P
P
G
R
A
G
S
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
G36
E
E
M
E
Q
P
A
G
E
A
E
S
A
A
P
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
S36
A
I
I
G
P
N
G
S
G
K
S
N
L
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
Chicken
Gallus gallus
NP_989849
1274
145838
L53
N
E
A
G
A
P
R
L
M
I
T
H
I
V
N
Frog
Xenopus laevis
P50532
1290
146971
P36
D
A
L
Q
A
D
P
P
A
P
T
Q
E
S
N
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
P36
S
T
A
V
Q
S
S
P
P
P
A
L
N
D
G
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
K37
L
D
V
P
P
P
K
K
P
T
D
A
S
Q
G
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
P51
A
T
S
G
T
G
I
P
Q
P
S
K
M
K
A
Honey Bee
Apis mellifera
XP_396862
1282
148175
P36
D
D
I
Y
I
P
P
P
L
K
E
N
N
K
I
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
D44
R
H
K
E
G
S
K
D
P
E
E
E
L
Q
R
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
N55
Q
A
K
N
T
I
M
N
C
K
E
M
P
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
S36
L
V
M
R
N
F
K
S
Y
A
G
E
Q
R
V
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
Q108
R
D
H
K
S
Y
S
Q
S
P
P
R
S
P
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
13.3
N.A.
0
13.3
26.6
0
20
6.6
20
6.6
6.6
P-Site Similarity:
100
100
6.6
13.3
N.A.
26.6
26.6
N.A.
0
20
33.3
13.3
20
20
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
24
12
0
12
0
6
0
6
24
6
6
6
18
18
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
24
18
0
0
0
6
0
6
0
0
6
0
0
6
6
% D
% Glu:
6
24
12
24
12
0
0
0
6
6
30
24
6
0
0
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
18
6
6
6
18
18
0
12
0
0
0
18
% G
% His:
0
6
6
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
6
12
0
6
6
6
0
0
6
0
0
6
0
6
% I
% Lys:
0
0
12
6
0
0
18
6
0
18
0
6
0
12
0
% K
% Leu:
12
0
6
0
0
0
0
6
6
0
0
6
12
0
6
% L
% Met:
0
0
12
0
0
0
6
0
6
0
0
6
6
6
0
% M
% Asn:
6
0
0
6
6
6
0
6
0
0
0
12
12
0
12
% N
% Pro:
0
0
12
18
24
48
30
24
18
24
6
0
18
18
12
% P
% Gln:
6
0
0
6
12
0
0
6
6
0
0
6
6
12
0
% Q
% Arg:
12
0
0
6
0
0
6
0
12
12
0
6
0
6
6
% R
% Ser:
6
0
6
0
6
12
18
24
6
0
12
18
24
6
0
% S
% Thr:
6
12
0
0
12
0
0
0
0
6
24
0
0
0
6
% T
% Val:
0
6
6
6
0
0
0
0
0
0
0
0
0
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
6
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _