KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
23.03
Human Site:
S94
Identified Species:
31.67
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
S94
I
V
N
Q
N
F
K
S
Y
A
G
E
K
I
L
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
S94
I
V
N
Q
N
F
K
S
Y
A
G
E
K
I
L
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
Y94
V
N
Q
N
F
K
S
Y
A
G
E
K
I
L
G
Dog
Lupus familis
XP_535848
1288
147094
S94
I
V
N
Q
N
F
K
S
Y
A
G
E
K
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
A94
N
Q
N
F
K
S
Y
A
G
E
K
V
L
G
P
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
F94
E
G
A
E
D
R
T
F
A
R
V
I
V
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
P13
E
Q
I
A
M
M
K
P
K
G
Q
T
E
H
D
Chicken
Gallus gallus
NP_989849
1274
145838
K111
R
A
Q
K
I
R
S
K
K
L
S
V
L
I
H
Frog
Xenopus laevis
P50532
1290
146971
I94
K
S
Y
A
G
E
R
I
L
G
P
F
H
K
R
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
Y94
V
N
R
N
F
K
S
Y
A
G
E
Q
I
L
G
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
Q95
F
K
S
Y
A
G
E
Q
I
L
G
P
F
H
K
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
T109
S
S
I
N
S
A
Y
T
D
N
S
S
A
V
L
Honey Bee
Apis mellifera
XP_396862
1282
148175
M94
K
S
N
V
I
D
S
M
L
F
V
F
G
Y
R
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
S102
V
E
V
D
N
F
K
S
Y
F
G
K
A
S
I
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
S113
I
M
T
E
N
F
K
S
Y
A
G
K
V
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
H94
L
I
H
N
S
T
N
H
Q
N
L
D
S
A
G
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
S166
L
V
L
E
N
F
K
S
Y
A
G
K
Q
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
0
100
N.A.
6.6
0
N.A.
6.6
6.6
0
0
6.6
6.6
6.6
40
60
P-Site Similarity:
100
100
20
100
N.A.
13.3
13.3
N.A.
13.3
13.3
6.6
20
20
26.6
6.6
60
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
12
6
6
0
6
18
30
0
0
12
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
6
6
0
0
6
0
0
6
0
0
6
% D
% Glu:
12
6
0
18
0
6
6
0
0
6
12
18
6
0
0
% E
% Phe:
6
0
0
6
12
36
0
6
0
12
0
12
6
0
0
% F
% Gly:
0
6
0
0
6
6
0
0
6
24
42
0
6
12
24
% G
% His:
0
0
6
0
0
0
0
6
0
0
0
0
6
12
6
% H
% Ile:
24
6
12
0
12
0
0
6
6
0
0
6
12
24
6
% I
% Lys:
12
6
0
6
6
12
42
6
12
0
6
24
18
6
6
% K
% Leu:
12
0
6
0
0
0
0
0
12
12
6
0
12
12
30
% L
% Met:
0
6
0
0
6
6
0
6
0
0
0
0
0
0
0
% M
% Asn:
6
12
30
24
36
0
6
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
6
0
0
6
6
0
0
6
% P
% Gln:
0
12
12
18
0
0
0
6
6
0
6
6
6
0
0
% Q
% Arg:
6
0
6
0
0
12
6
0
0
6
0
0
0
0
12
% R
% Ser:
6
18
6
0
12
6
24
36
0
0
12
6
6
6
0
% S
% Thr:
0
0
6
0
0
6
6
6
0
0
0
6
0
0
0
% T
% Val:
18
24
6
6
0
0
0
0
0
0
12
12
12
18
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
6
0
0
12
12
36
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _