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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
23.03
Human Site:
S982
Identified Species:
31.67
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
S982
N
T
N
A
A
E
E
S
L
P
E
I
Q
K
E
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
S982
N
T
N
A
A
E
E
S
L
P
E
I
Q
K
E
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
S981
N
T
N
A
A
E
E
S
L
P
E
I
Q
K
E
Dog
Lupus familis
XP_535848
1288
147094
S982
N
T
T
A
A
E
E
S
L
P
E
I
Q
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
S980
N
T
K
T
A
E
T
S
L
P
E
I
Q
K
E
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
K918
E
V
T
A
I
E
T
K
L
E
Q
K
R
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
L791
A
L
S
I
R
L
K
L
E
Q
I
D
S
H
I
Chicken
Gallus gallus
NP_989849
1274
145838
A953
D
C
R
Q
A
E
E
A
L
P
G
V
Q
E
E
Frog
Xenopus laevis
P50532
1290
146971
S976
E
C
K
E
A
E
C
S
L
P
E
V
Q
E
Q
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
A981
S
T
S
S
A
E
K
A
L
P
E
V
Q
D
Q
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
S977
A
C
Q
E
S
E
A
S
L
P
E
V
Q
E
Q
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
L1323
S
L
V
K
V
E
E
L
V
K
V
L
E
E
K
Honey Bee
Apis mellifera
XP_396862
1282
148175
A919
K
L
D
E
L
T
E
A
L
S
E
R
D
E
A
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
I995
V
E
R
F
E
K
Q
I
K
K
L
Q
T
K
G
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
Q980
E
F
K
E
S
E
I
Q
L
K
E
M
E
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L924
T
Y
K
K
T
Q
Q
L
I
D
E
H
K
D
V
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
L1057
N
M
N
E
T
L
N
L
K
V
E
L
K
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
100
93.3
N.A.
80
20
N.A.
0
46.6
46.6
46.6
40
13.3
20
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
40
N.A.
13.3
73.3
66.6
93.3
66.6
53.3
40
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
30
48
0
6
18
0
0
0
0
0
0
6
% A
% Cys:
0
18
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
6
0
0
0
0
0
0
6
0
6
6
12
6
% D
% Glu:
18
6
0
30
6
71
42
0
6
6
71
0
12
36
36
% E
% Phe:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
6
0
0
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
6
0
6
0
% H
% Ile:
0
0
0
6
6
0
6
6
6
0
6
30
0
0
6
% I
% Lys:
6
0
24
12
0
6
12
6
12
18
0
6
12
36
6
% K
% Leu:
0
18
0
0
6
12
0
24
71
0
6
12
0
0
0
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
36
0
24
0
0
0
6
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
53
0
0
0
0
0
% P
% Gln:
0
0
6
6
0
6
12
6
0
6
6
6
53
0
24
% Q
% Arg:
0
0
12
0
6
0
0
0
0
0
0
6
6
0
0
% R
% Ser:
12
0
12
6
12
0
0
42
0
6
0
0
6
6
0
% S
% Thr:
6
36
12
6
12
6
12
0
0
0
0
0
6
0
6
% T
% Val:
6
6
6
0
6
0
0
0
6
6
6
24
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _