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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SACM1L All Species: 33.94
Human Site: S51 Identified Species: 53.33
UniProt: Q9NTJ5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTJ5 NP_054735.3 587 66967 S51 V K K D V P P S A V T R P I F
Chimpanzee Pan troglodytes XP_516409 577 66023 S51 V K K D V P P S A V T R P I F
Rhesus Macaque Macaca mulatta XP_001114514 587 66967 S51 V K K D V P P S A V T R P I F
Dog Lupus familis XP_541911 587 67028 S51 V K K D I P P S A V T R P I F
Cat Felis silvestris
Mouse Mus musculus Q9EP69 587 66925 S51 V K K D V P P S A V T R P I F
Rat Rattus norvegicus Q9ES21 587 67020 S51 V K K D V P P S A V T R P I Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513569 619 70356 S83 V K K D V P P S A V T R P I F
Chicken Gallus gallus XP_418799 601 68303 S57 V K K D V P P S A V T R P I F
Frog Xenopus laevis Q6GM29 586 66938 A51 K K D I P P S A I T R A I Y G
Zebra Danio Brachydanio rerio A1L244 586 66913 A51 R K D V P P S A V T R P I C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0I6 592 67749 L55 S G G L V A N L R P T R R I C
Honey Bee Apis mellifera XP_623141 584 67372 T53 T A S Q I P S T A S R R K I W
Nematode Worm Caenorhab. elegans NP_492518 591 68110 D56 K Q R V P I A D T D I K F I Y
Sea Urchin Strong. purpuratus XP_001202593 432 49658
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32368 623 71106 A56 Q G E V V K I A S L M G F I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 99.1 94.3 N.A. 95 95 N.A. 83.3 79.1 83.4 80 N.A. 45.9 48.2 46.8 43.1
Protein Similarity: 100 97.9 99.6 97.6 N.A. 98.1 98.3 N.A. 90.1 85.5 91.6 88.2 N.A. 65.3 70 64.1 56.5
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 100 100 13.3 13.3 N.A. 26.6 26.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 20 N.A. 26.6 46.6 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 7 7 20 60 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % C
% Asp: 0 0 14 54 0 0 0 7 0 7 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 47 % F
% Gly: 0 14 7 0 0 0 0 0 0 0 0 7 0 0 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 14 7 7 0 7 0 7 0 14 80 0 % I
% Lys: 14 67 54 0 0 7 0 0 0 0 0 7 7 0 7 % K
% Leu: 0 0 0 7 0 0 0 7 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 20 74 54 0 0 7 0 7 54 0 0 % P
% Gln: 7 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 7 0 0 0 0 0 7 0 20 67 7 0 0 % R
% Ser: 7 0 7 0 0 0 20 54 7 7 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 7 7 14 60 0 0 0 0 % T
% Val: 54 0 0 20 60 0 0 0 7 54 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _