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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SACM1L
All Species:
42.42
Human Site:
Y246
Identified Species:
66.67
UniProt:
Q9NTJ5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ5
NP_054735.3
587
66967
Y246
E
T
E
Q
I
V
H
Y
N
G
S
K
A
S
F
Chimpanzee
Pan troglodytes
XP_516409
577
66023
Y246
E
T
E
Q
I
V
H
Y
N
G
S
K
A
S
F
Rhesus Macaque
Macaca mulatta
XP_001114514
587
66967
Y246
E
T
E
Q
I
V
H
Y
N
G
S
K
A
S
F
Dog
Lupus familis
XP_541911
587
67028
Y246
E
T
E
Q
I
V
H
Y
N
G
S
R
A
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP69
587
66925
Y246
E
T
E
Q
I
V
H
Y
S
G
N
R
A
S
F
Rat
Rattus norvegicus
Q9ES21
587
67020
Y246
E
T
E
Q
I
V
H
Y
S
G
N
R
A
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513569
619
70356
Y278
E
T
E
Q
I
V
H
Y
N
G
S
R
A
S
F
Chicken
Gallus gallus
XP_418799
601
68303
Y252
E
T
E
Q
I
V
H
Y
K
G
S
K
A
S
F
Frog
Xenopus laevis
Q6GM29
586
66938
Y245
E
T
E
Q
I
V
H
Y
N
G
N
K
A
S
F
Zebra Danio
Brachydanio rerio
A1L244
586
66913
Y245
E
T
E
Q
I
I
Q
Y
N
G
A
K
A
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0I6
592
67749
F245
E
T
E
Q
I
V
E
F
N
G
Q
L
T
G
F
Honey Bee
Apis mellifera
XP_623141
584
67372
F249
E
T
E
Q
L
V
E
F
N
G
H
R
M
S
F
Nematode Worm
Caenorhab. elegans
NP_492518
591
68110
Y252
E
T
E
Q
I
V
E
Y
T
N
P
D
K
H
L
Sea Urchin
Strong. purpuratus
XP_001202593
432
49658
Q121
V
P
H
I
S
E
S
Q
S
H
L
D
A
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32368
623
71106
E243
I
L
L
A
E
N
P
E
S
E
K
I
H
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.1
94.3
N.A.
95
95
N.A.
83.3
79.1
83.4
80
N.A.
45.9
48.2
46.8
43.1
Protein Similarity:
100
97.9
99.6
97.6
N.A.
98.1
98.3
N.A.
90.1
85.5
91.6
88.2
N.A.
65.3
70
64.1
56.5
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
93.3
93.3
93.3
80
N.A.
60
60
46.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
66.6
80
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
7
0
74
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% D
% Glu:
87
0
87
0
7
7
20
7
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
0
0
7
87
% F
% Gly:
0
0
0
0
0
0
0
0
0
80
0
0
0
7
0
% G
% His:
0
0
7
0
0
0
60
0
0
7
7
0
7
7
0
% H
% Ile:
7
0
0
7
80
7
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
7
0
7
40
7
0
7
% K
% Leu:
0
7
7
0
7
0
0
0
0
0
7
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
60
7
20
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
7
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
87
0
0
7
7
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% R
% Ser:
0
0
0
0
7
0
7
0
27
0
40
0
0
74
0
% S
% Thr:
0
87
0
0
0
0
0
0
7
0
0
0
7
0
0
% T
% Val:
7
0
0
0
0
80
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _