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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SACM1L All Species: 44.85
Human Site: Y272 Identified Species: 70.48
UniProt: Q9NTJ5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTJ5 NP_054735.3 587 66967 Y272 S Q R P N L K Y K P L P Q I S
Chimpanzee Pan troglodytes XP_516409 577 66023 Y272 S Q R P N L K Y K P L P Q I S
Rhesus Macaque Macaca mulatta XP_001114514 587 66967 Y272 S Q R P N L K Y K P L P Q I S
Dog Lupus familis XP_541911 587 67028 Y272 S Q R P N L K Y K P Q P L I N
Cat Felis silvestris
Mouse Mus musculus Q9EP69 587 66925 Y272 S Q R P N L K Y K P H P Q I S
Rat Rattus norvegicus Q9ES21 587 67020 Y272 S Q R P N L K Y K P D P Q I N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513569 619 70356 Y304 S Q R P N L K Y K P K P Q I N
Chicken Gallus gallus XP_418799 601 68303 Y278 S Q R P N L K Y K P K P Q I S
Frog Xenopus laevis Q6GM29 586 66938 Y271 S Q R P N L K Y K P K P Q I S
Zebra Danio Brachydanio rerio A1L244 586 66913 Y271 S Q R P N L K Y K P K P Q I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0I6 592 67749 Y271 H Q L P N L R Y K P R P V L V
Honey Bee Apis mellifera XP_623141 584 67372 Y275 Y Q A P N L K Y K P K P Q L G
Nematode Worm Caenorhab. elegans NP_492518 591 68110 N278 L L W T Q K P N L R W Q P M P
Sea Urchin Strong. purpuratus XP_001202593 432 49658 I147 N Q V L I N L I D H K G A E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32368 623 71106 L269 Y W A E I N N L K Y K P N L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 99.1 94.3 N.A. 95 95 N.A. 83.3 79.1 83.4 80 N.A. 45.9 48.2 46.8 43.1
Protein Similarity: 100 97.9 99.6 97.6 N.A. 98.1 98.3 N.A. 90.1 85.5 91.6 88.2 N.A. 65.3 70 64.1 56.5
P-Site Identity: 100 100 100 80 N.A. 93.3 86.6 N.A. 86.6 93.3 93.3 93.3 N.A. 53.3 66.6 0 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 93.3 N.A. 66.6 73.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 0 0 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % G
% His: 7 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 0 0 0 0 14 0 0 7 0 0 0 0 0 67 0 % I
% Lys: 0 0 0 0 0 7 74 0 87 0 47 0 0 0 0 % K
% Leu: 7 7 7 7 0 80 7 7 7 0 20 0 7 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 80 14 7 7 0 0 0 0 7 0 27 % N
% Pro: 0 0 0 80 0 0 7 0 0 80 0 87 7 0 7 % P
% Gln: 0 87 0 0 7 0 0 0 0 0 7 7 67 0 0 % Q
% Arg: 0 0 67 0 0 0 7 0 0 7 7 0 0 0 0 % R
% Ser: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % S
% Thr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 14 % V
% Trp: 0 7 7 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 14 0 0 0 0 0 0 80 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _