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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC1
All Species:
5.15
Human Site:
S18
Identified Species:
10.3
UniProt:
Q9NTX5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTX5
NP_001002030.1
307
33698
S18
L
L
K
T
A
S
L
S
G
R
T
K
L
L
H
Chimpanzee
Pan troglodytes
NP_001092043
301
32983
K16
A
S
L
S
G
R
T
K
L
L
H
Q
T
G
L
Rhesus Macaque
Macaca mulatta
XP_001106197
301
33039
K16
S
S
L
S
G
R
T
K
L
L
H
Q
T
G
L
Dog
Lupus familis
XP_851564
307
33271
S18
L
L
K
T
S
S
L
S
V
R
T
K
L
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9V3
322
35449
L33
K
C
L
L
T
S
S
L
S
V
R
T
K
L
L
Rat
Rattus norvegicus
Q6AYG5
299
32612
Q18
S
V
R
T
K
I
L
Q
T
G
V
S
L
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505944
268
29542
Chicken
Gallus gallus
XP_001231583
284
30799
Y16
L
Y
N
G
A
H
D
Y
D
E
E
L
I
K
K
Frog
Xenopus laevis
NP_001088953
299
32637
R16
S
L
S
M
T
N
I
R
W
L
H
H
R
C
L
Zebra Danio
Brachydanio rerio
NP_001018399
164
17911
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491222
268
29133
Sea Urchin
Strong. purpuratus
XP_789370
227
24712
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96
80.4
N.A.
76.7
79.4
N.A.
51.4
60.5
55.7
29.9
N.A.
N.A.
N.A.
26
30.2
Protein Similarity:
100
98
97.3
91.2
N.A.
86.3
88.2
N.A.
62.5
74.2
75.2
40
N.A.
N.A.
N.A.
47.2
47.2
P-Site Identity:
100
0
0
86.6
N.A.
13.3
20
N.A.
0
13.3
6.6
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
13.3
40
N.A.
0
20
20
0
N.A.
N.A.
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
17
0
0
0
9
9
0
0
0
17
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
25
9
0
0
17
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% I
% Lys:
9
0
17
0
9
0
0
17
0
0
0
17
9
9
9
% K
% Leu:
25
25
25
9
0
0
25
9
17
25
0
9
25
25
34
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
17
0
0
0
% Q
% Arg:
0
0
9
0
0
17
0
9
0
17
9
0
9
0
0
% R
% Ser:
25
17
9
17
9
25
9
17
9
0
0
9
0
0
0
% S
% Thr:
0
0
0
25
17
0
17
0
9
0
17
9
17
0
0
% T
% Val:
0
9
0
0
0
0
0
0
9
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _