KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC1
All Species:
22.73
Human Site:
S213
Identified Species:
45.45
UniProt:
Q9NTX5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTX5
NP_001002030.1
307
33698
S213
R
Q
A
L
K
V
L
S
G
A
L
K
L
D
S
Chimpanzee
Pan troglodytes
NP_001092043
301
32983
S207
R
Q
A
L
K
V
L
S
G
A
L
K
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001106197
301
33039
S207
R
Q
A
L
K
V
L
S
G
A
L
K
L
D
S
Dog
Lupus familis
XP_851564
307
33271
S213
R
Q
A
L
K
V
L
S
G
A
L
P
L
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9V3
322
35449
S228
R
Q
A
L
K
V
L
S
G
T
L
K
L
D
S
Rat
Rattus norvegicus
Q6AYG5
299
32612
D211
L
S
G
T
F
K
L
D
S
K
E
A
L
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505944
268
29542
S196
L
V
E
E
I
L
R
S
S
D
E
A
D
S
L
Chicken
Gallus gallus
XP_001231583
284
30799
S207
R
A
L
H
L
G
L
S
E
G
T
L
S
S
S
Frog
Xenopus laevis
NP_001088953
299
32637
S207
R
H
A
L
K
L
L
S
G
A
P
R
V
Q
P
Zebra Danio
Brachydanio rerio
NP_001018399
164
17911
E92
N
E
L
E
I
W
T
E
G
K
A
V
I
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491222
268
29133
Q196
S
A
E
E
A
K
D
Q
G
Y
V
D
Y
V
Y
Sea Urchin
Strong. purpuratus
XP_789370
227
24712
L154
M
G
L
A
D
D
V
L
P
S
S
S
D
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96
80.4
N.A.
76.7
79.4
N.A.
51.4
60.5
55.7
29.9
N.A.
N.A.
N.A.
26
30.2
Protein Similarity:
100
98
97.3
91.2
N.A.
86.3
88.2
N.A.
62.5
74.2
75.2
40
N.A.
N.A.
N.A.
47.2
47.2
P-Site Identity:
100
100
100
86.6
N.A.
93.3
13.3
N.A.
6.6
26.6
53.3
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
13.3
26.6
73.3
20
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
50
9
9
0
0
0
0
42
9
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
9
9
0
9
0
9
17
42
0
% D
% Glu:
0
9
17
25
0
0
0
9
9
0
17
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
9
0
0
67
9
0
0
0
0
0
% G
% His:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
0
0
0
0
0
9
0
9
% I
% Lys:
0
0
0
0
50
17
0
0
0
17
0
34
0
0
0
% K
% Leu:
17
0
25
50
9
17
67
9
0
0
42
9
50
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
9
% P
% Gln:
0
42
0
0
0
0
0
9
0
0
0
0
0
9
9
% Q
% Arg:
59
0
0
0
0
0
9
0
0
0
0
9
0
9
0
% R
% Ser:
9
9
0
0
0
0
0
67
17
9
9
9
9
25
42
% S
% Thr:
0
0
0
9
0
0
9
0
0
9
9
0
0
0
0
% T
% Val:
0
9
0
0
0
42
9
0
0
0
9
9
9
17
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _