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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC1
All Species:
25.45
Human Site:
T288
Identified Species:
50.91
UniProt:
Q9NTX5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTX5
NP_001002030.1
307
33698
T288
N
E
R
D
L
L
G
T
V
W
G
G
P
A
N
Chimpanzee
Pan troglodytes
NP_001092043
301
32983
T282
N
E
R
D
L
L
G
T
V
W
G
G
P
A
N
Rhesus Macaque
Macaca mulatta
XP_001106197
301
33039
T282
N
E
R
D
L
L
G
T
V
W
G
G
P
A
N
Dog
Lupus familis
XP_851564
307
33271
T288
M
E
K
E
L
V
G
T
V
W
G
G
P
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9V3
322
35449
T303
N
E
R
D
V
L
E
T
L
W
G
G
P
A
N
Rat
Rattus norvegicus
Q6AYG5
299
32612
T280
N
E
R
D
V
L
E
T
L
W
G
G
P
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505944
268
29542
E261
P
A
N
L
K
A
L
E
K
K
G
K
F
N
K
Chicken
Gallus gallus
XP_001231583
284
30799
N273
T
V
W
G
G
P
A
N
L
E
A
L
T
R
R
Frog
Xenopus laevis
NP_001088953
299
32637
T281
T
E
K
E
I
F
G
T
V
W
G
G
L
A
N
Zebra Danio
Brachydanio rerio
NP_001018399
164
17911
R157
G
R
K
S
S
G
W
R
S
R
T
H
H
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491222
268
29133
Q261
H
R
N
A
L
Q
K
Q
L
E
A
V
V
K
K
Sea Urchin
Strong. purpuratus
XP_789370
227
24712
K219
P
E
H
V
E
K
F
K
N
V
L
E
K
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96
80.4
N.A.
76.7
79.4
N.A.
51.4
60.5
55.7
29.9
N.A.
N.A.
N.A.
26
30.2
Protein Similarity:
100
98
97.3
91.2
N.A.
86.3
88.2
N.A.
62.5
74.2
75.2
40
N.A.
N.A.
N.A.
47.2
47.2
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
6.6
0
60
0
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
80
6.6
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
9
0
0
0
17
0
0
59
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
67
0
17
9
0
17
9
0
17
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
9
9
9
42
0
0
0
67
59
0
0
0
% G
% His:
9
0
9
0
0
0
0
0
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
25
0
9
9
9
9
9
9
0
9
9
9
17
% K
% Leu:
0
0
0
9
42
42
9
0
34
0
9
9
9
9
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
0
17
0
0
0
0
9
9
0
0
0
0
9
59
% N
% Pro:
17
0
0
0
0
9
0
0
0
0
0
0
50
0
0
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
17
42
0
0
0
0
9
0
9
0
0
0
17
9
% R
% Ser:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% S
% Thr:
17
0
0
0
0
0
0
59
0
0
9
0
9
0
0
% T
% Val:
0
9
0
9
17
9
0
0
42
9
0
9
9
0
0
% V
% Trp:
0
0
9
0
0
0
9
0
0
59
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _