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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC1
All Species:
1.21
Human Site:
T46
Identified Species:
2.42
UniProt:
Q9NTX5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTX5
NP_001002030.1
307
33698
T46
Y
E
E
E
V
K
K
T
L
Q
Q
F
P
G
G
Chimpanzee
Pan troglodytes
NP_001092043
301
32983
F44
M
K
K
T
L
Q
Q
F
P
G
G
S
I
D
L
Rhesus Macaque
Macaca mulatta
XP_001106197
301
33039
F44
V
K
K
K
L
Q
Q
F
P
G
G
S
I
D
L
Dog
Lupus familis
XP_851564
307
33271
K46
H
E
E
D
L
K
K
K
L
Q
Q
F
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9V3
322
35449
I61
H
E
E
E
V
K
K
I
L
E
Q
F
P
G
G
Rat
Rattus norvegicus
Q6AYG5
299
32612
S46
L
E
Q
F
P
G
G
S
I
D
L
Q
K
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505944
268
29542
P33
R
Q
D
L
C
L
I
P
T
E
L
S
A
A
R
Chicken
Gallus gallus
XP_001231583
284
30799
I44
K
E
H
S
G
I
G
I
L
T
L
N
N
S
R
Frog
Xenopus laevis
NP_001088953
299
32637
F44
I
K
K
K
L
A
Q
F
T
G
G
S
V
D
L
Zebra Danio
Brachydanio rerio
NP_001018399
164
17911
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491222
268
29133
K33
V
Q
R
N
E
K
L
K
T
R
L
D
V
I
L
Sea Urchin
Strong. purpuratus
XP_789370
227
24712
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96
80.4
N.A.
76.7
79.4
N.A.
51.4
60.5
55.7
29.9
N.A.
N.A.
N.A.
26
30.2
Protein Similarity:
100
98
97.3
91.2
N.A.
86.3
88.2
N.A.
62.5
74.2
75.2
40
N.A.
N.A.
N.A.
47.2
47.2
P-Site Identity:
100
0
0
73.3
N.A.
80
6.6
N.A.
0
13.3
0
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
33.3
40
93.3
N.A.
93.3
26.6
N.A.
20
13.3
33.3
0
N.A.
N.A.
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
0
0
9
0
9
0
25
0
% D
% Glu:
0
42
25
17
9
0
0
0
0
17
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
25
0
0
0
25
0
0
0
% F
% Gly:
0
0
0
0
9
9
17
0
0
25
25
0
0
25
25
% G
% His:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
9
17
9
0
0
0
17
9
0
% I
% Lys:
9
25
25
17
0
34
25
17
0
0
0
0
9
9
0
% K
% Leu:
9
0
0
9
34
9
9
0
34
0
34
0
0
0
34
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% N
% Pro:
0
0
0
0
9
0
0
9
17
0
0
0
25
0
0
% P
% Gln:
0
17
9
0
0
17
25
0
0
17
25
9
0
0
9
% Q
% Arg:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
17
% R
% Ser:
0
0
0
9
0
0
0
9
0
0
0
34
0
9
0
% S
% Thr:
0
0
0
9
0
0
0
9
25
9
0
0
0
0
0
% T
% Val:
17
0
0
0
17
0
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _