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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC1
All Species:
18.48
Human Site:
Y274
Identified Species:
36.97
UniProt:
Q9NTX5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTX5
NP_001002030.1
307
33698
Y274
V
C
S
G
R
E
L
Y
L
E
E
A
L
Q
N
Chimpanzee
Pan troglodytes
NP_001092043
301
32983
Y268
V
C
S
G
R
E
L
Y
L
E
E
A
L
Q
N
Rhesus Macaque
Macaca mulatta
XP_001106197
301
33039
Y268
V
C
S
G
R
E
L
Y
L
E
E
A
L
Q
N
Dog
Lupus familis
XP_851564
307
33271
C274
V
S
S
S
R
E
L
C
L
E
E
A
L
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9V3
322
35449
Y289
V
C
S
A
R
E
L
Y
I
E
E
A
L
Q
N
Rat
Rattus norvegicus
Q6AYG5
299
32612
Y266
V
C
S
G
R
E
L
Y
L
E
E
A
L
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505944
268
29542
L247
L
Q
T
E
R
D
V
L
G
T
V
W
A
G
P
Chicken
Gallus gallus
XP_001231583
284
30799
T259
P
L
E
A
A
L
R
T
E
K
D
V
F
G
T
Frog
Xenopus laevis
NP_001088953
299
32637
N267
I
I
S
G
R
E
Q
N
L
E
D
A
L
R
T
Zebra Danio
Brachydanio rerio
NP_001018399
164
17911
A143
R
L
L
R
Q
A
A
A
H
L
C
G
S
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491222
268
29133
A247
E
Q
K
Q
V
L
E
A
V
W
N
G
E
T
H
Sea Urchin
Strong. purpuratus
XP_789370
227
24712
F205
L
K
V
E
R
E
I
F
T
S
C
W
C
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96
80.4
N.A.
76.7
79.4
N.A.
51.4
60.5
55.7
29.9
N.A.
N.A.
N.A.
26
30.2
Protein Similarity:
100
98
97.3
91.2
N.A.
86.3
88.2
N.A.
62.5
74.2
75.2
40
N.A.
N.A.
N.A.
47.2
47.2
P-Site Identity:
100
100
100
73.3
N.A.
86.6
100
N.A.
6.6
0
53.3
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
100
N.A.
33.3
13.3
73.3
6.6
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
9
9
17
0
0
0
59
9
0
0
% A
% Cys:
0
42
0
0
0
0
0
9
0
0
17
0
9
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% D
% Glu:
9
0
9
17
0
67
9
0
9
59
50
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
42
0
0
0
0
9
0
0
17
0
25
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% H
% Ile:
9
9
0
0
0
0
9
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
17
17
9
0
0
17
50
9
50
9
0
0
59
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
42
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
17
0
9
9
0
9
0
0
0
0
0
0
50
0
% Q
% Arg:
9
0
0
9
75
0
9
0
0
0
0
0
0
9
0
% R
% Ser:
0
9
59
9
0
0
0
0
0
9
0
0
9
9
0
% S
% Thr:
0
0
9
0
0
0
0
9
9
9
0
0
0
9
17
% T
% Val:
50
0
9
0
9
0
9
0
9
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
17
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _