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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF146 All Species: 10
Human Site: S203 Identified Species: 24.44
UniProt: Q9NTX7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTX7 NP_112225.2 359 38950 S203 S S A D G A D S V S A Q S G A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106451 359 38833 S202 S S A D G A D S V S A Q S G A
Dog Lupus familis XP_533493 358 38546 S202 S S A D G A D S V P A Q S G A
Cat Felis silvestris
Mouse Mus musculus Q9CZW6 359 38916 D203 E S S A D G A D S G S A Q T G
Rat Rattus norvegicus Q5XIK5 352 38206 S196 V N L A R E S S A D G A D S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423089 352 38139 S196 V N L A R E S S A D G A D S T
Frog Xenopus laevis NP_001085469 314 34753 H159 V Q Y R R N E H G R R R K I K
Zebra Danio Brachydanio rerio NP_956148 364 38767 A208 A G A V P A P A V V D V S V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623395 287 32639 K132 E T A Y K Q G K R N C E L L I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782343 417 46375 H243 A V S P N A N H S N S A G N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.3 91.3 N.A. 92.7 89.9 N.A. N.A. 83.8 61.2 47.7 N.A. N.A. 37.3 N.A. 34.5
Protein Similarity: 100 N.A. 99.1 94.7 N.A. 94.9 93.5 N.A. N.A. 89.6 70.1 61.5 N.A. N.A. 52.6 N.A. 50.1
P-Site Identity: 100 N.A. 100 93.3 N.A. 6.6 6.6 N.A. N.A. 6.6 0 26.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 20 13.3 N.A. N.A. 13.3 13.3 40 N.A. N.A. 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 50 30 0 50 10 10 20 0 30 40 0 0 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 30 10 0 30 10 0 20 10 0 20 0 10 % D
% Glu: 20 0 0 0 0 20 10 0 0 0 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 30 10 10 0 10 10 20 0 10 30 20 % G
% His: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 0 10 0 0 10 0 0 0 0 10 0 10 % K
% Leu: 0 0 20 0 0 0 0 0 0 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 10 10 10 0 0 20 0 0 0 10 0 % N
% Pro: 0 0 0 10 10 0 10 0 0 10 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 10 0 0 0 0 0 30 10 0 0 % Q
% Arg: 0 0 0 10 30 0 0 0 10 10 10 10 0 0 0 % R
% Ser: 30 40 20 0 0 0 20 50 20 20 20 0 40 20 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 30 10 0 10 0 0 0 0 40 10 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _