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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF146
All Species:
1.52
Human Site:
T257
Identified Species:
3.7
UniProt:
Q9NTX7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTX7
NP_112225.2
359
38950
T257
L
Q
L
S
G
D
N
T
A
E
R
S
H
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106451
359
38833
I256
L
Q
L
S
G
D
S
I
A
E
R
S
H
R
G
Dog
Lupus familis
XP_533493
358
38546
I256
L
H
L
G
G
D
S
I
A
E
R
S
H
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZW6
359
38916
D257
A
H
L
Q
L
S
G
D
S
I
A
E
R
S
H
Rat
Rattus norvegicus
Q5XIK5
352
38206
L250
L
E
D
S
F
A
H
L
Q
L
S
G
D
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423089
352
38139
L250
L
E
N
S
F
A
H
L
Q
I
N
G
D
S
M
Frog
Xenopus laevis
NP_001085469
314
34753
P213
L
G
D
S
S
S
Q
P
A
H
V
L
P
A
R
Zebra Danio
Brachydanio rerio
NP_956148
364
38767
S262
H
L
T
S
P
A
S
S
S
D
I
Q
L
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623395
287
32639
D186
G
L
R
L
N
N
Q
D
E
E
I
T
R
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782343
417
46375
R297
Y
A
K
P
I
R
Q
R
R
R
P
A
N
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
91.3
N.A.
92.7
89.9
N.A.
N.A.
83.8
61.2
47.7
N.A.
N.A.
37.3
N.A.
34.5
Protein Similarity:
100
N.A.
99.1
94.7
N.A.
94.9
93.5
N.A.
N.A.
89.6
70.1
61.5
N.A.
N.A.
52.6
N.A.
50.1
P-Site Identity:
100
N.A.
86.6
73.3
N.A.
6.6
13.3
N.A.
N.A.
13.3
20
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
N.A.
93.3
80
N.A.
13.3
26.6
N.A.
N.A.
26.6
20
33.3
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
30
0
0
40
0
10
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
30
0
20
0
10
0
0
20
0
0
% D
% Glu:
0
20
0
0
0
0
0
0
10
40
0
10
0
20
0
% E
% Phe:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
30
0
10
0
0
0
0
20
0
0
30
% G
% His:
10
20
0
0
0
0
20
0
0
10
0
0
30
0
10
% H
% Ile:
0
0
0
0
10
0
0
20
0
20
20
0
0
0
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
60
20
40
10
10
0
0
20
0
10
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
10
10
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
10
10
0
0
10
0
0
10
0
10
0
0
% P
% Gln:
0
20
0
10
0
0
30
0
20
0
0
10
0
0
10
% Q
% Arg:
0
0
10
0
0
10
0
10
10
10
30
0
20
30
10
% R
% Ser:
0
0
0
60
10
20
30
10
20
0
10
30
0
30
10
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _