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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22B
All Species:
18.18
Human Site:
S154
Identified Species:
36.36
UniProt:
Q9NU19
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NU19
NP_060242.2
505
59081
S154
N
P
L
H
K
Q
Q
S
L
P
L
R
P
I
I
Chimpanzee
Pan troglodytes
XP_527375
505
59106
S154
N
P
L
H
K
Q
Q
S
L
P
L
R
P
I
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538894
488
57073
A155
A
R
I
S
D
Q
N
A
S
G
A
P
P
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
Q165
T
V
P
L
Q
R
S
Q
S
L
P
H
S
A
T
Rat
Rattus norvegicus
NP_001020230
505
59036
S154
N
T
L
H
K
Q
Q
S
L
P
L
R
P
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
L156
P
L
R
P
I
I
P
L
V
A
R
I
S
D
Q
Chicken
Gallus gallus
XP_419261
747
85990
S396
T
P
L
Q
K
Q
Q
S
L
P
L
R
P
I
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685523
523
60664
S172
N
P
L
Q
K
Q
Q
S
L
P
V
R
P
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650941
546
61493
S190
D
R
R
S
L
P
D
S
N
E
N
R
S
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
R154
A
P
P
H
G
G
D
R
D
Q
T
R
F
A
R
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
R156
P
R
P
S
S
P
I
R
I
S
T
I
P
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
L224
T
Y
P
Q
L
P
Q
L
Q
K
E
K
T
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
95.4
N.A.
62.2
98.4
N.A.
79.6
63.3
N.A.
70.1
N.A.
43
N.A.
46.9
46.7
Protein Similarity:
100
100
N.A.
96
N.A.
76.7
99
N.A.
83.5
65.1
N.A.
81.6
N.A.
57.6
N.A.
62.1
65.5
P-Site Identity:
100
100
N.A.
13.3
N.A.
0
93.3
N.A.
0
86.6
N.A.
80
N.A.
13.3
N.A.
20
6.6
P-Site Similarity:
100
100
N.A.
33.3
N.A.
13.3
93.3
N.A.
6.6
86.6
N.A.
93.3
N.A.
26.6
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
9
0
9
9
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
17
0
9
0
0
0
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
34
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
9
0
9
9
9
0
9
0
0
17
0
34
42
% I
% Lys:
0
0
0
0
42
0
0
0
0
9
0
9
0
0
0
% K
% Leu:
0
9
42
9
17
0
0
17
42
9
34
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
34
0
0
0
0
0
9
0
9
0
9
0
0
9
0
% N
% Pro:
17
42
34
9
0
25
9
0
0
42
9
9
59
0
0
% P
% Gln:
0
0
0
25
9
50
50
9
9
9
0
0
0
0
9
% Q
% Arg:
0
25
17
0
0
9
0
17
0
0
9
59
0
9
9
% R
% Ser:
0
0
0
25
9
0
9
50
17
9
0
0
25
0
9
% S
% Thr:
25
9
0
0
0
0
0
0
0
0
17
0
9
0
17
% T
% Val:
0
9
0
0
0
0
0
0
9
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _