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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22B
All Species:
20.61
Human Site:
S340
Identified Species:
41.21
UniProt:
Q9NU19
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NU19
NP_060242.2
505
59081
S340
N
F
D
V
T
N
L
S
Q
D
M
L
R
S
I
Chimpanzee
Pan troglodytes
XP_527375
505
59106
S340
N
F
D
V
T
N
L
S
Q
D
M
L
R
S
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538894
488
57073
M326
V
T
N
L
S
Q
D
M
L
R
S
I
E
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
P351
K
V
D
V
S
S
V
P
A
E
V
L
R
N
I
Rat
Rattus norvegicus
NP_001020230
505
59036
S340
N
F
D
V
T
N
L
S
Q
D
M
L
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
S333
N
F
D
V
T
N
L
S
Q
D
V
L
R
S
I
Chicken
Gallus gallus
XP_419261
747
85990
S582
N
F
D
V
T
N
L
S
Q
D
V
L
R
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685523
523
60664
P358
N
F
E
M
A
S
L
P
L
D
T
Q
R
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650941
546
61493
P379
K
Y
D
M
S
T
L
P
E
E
T
R
N
I
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
P325
S
F
D
V
S
Q
L
P
L
E
Q
C
Q
L
I
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
S329
Y
K
G
I
N
K
L
S
K
K
I
L
R
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
V414
K
D
P
S
T
Y
M
V
D
E
Q
I
T
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
95.4
N.A.
62.2
98.4
N.A.
79.6
63.3
N.A.
70.1
N.A.
43
N.A.
46.9
46.7
Protein Similarity:
100
100
N.A.
96
N.A.
76.7
99
N.A.
83.5
65.1
N.A.
81.6
N.A.
57.6
N.A.
62.1
65.5
P-Site Identity:
100
100
N.A.
0
N.A.
33.3
100
N.A.
93.3
93.3
N.A.
40
N.A.
20
N.A.
33.3
33.3
P-Site Similarity:
100
100
N.A.
33.3
N.A.
73.3
100
N.A.
100
100
N.A.
66.6
N.A.
53.3
N.A.
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
67
0
0
0
9
0
9
50
0
0
0
9
9
% D
% Glu:
0
0
9
0
0
0
0
0
9
34
0
0
9
9
0
% E
% Phe:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
17
0
9
84
% I
% Lys:
25
9
0
0
0
9
0
0
9
9
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
75
0
25
0
0
59
0
9
9
% L
% Met:
0
0
0
17
0
0
9
9
0
0
25
0
0
0
0
% M
% Asn:
50
0
9
0
9
42
0
0
0
0
0
0
9
17
0
% N
% Pro:
0
0
9
0
0
0
0
34
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
42
0
17
9
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
9
67
0
0
% R
% Ser:
9
0
0
9
34
17
0
50
0
0
9
0
0
42
0
% S
% Thr:
0
9
0
0
50
9
0
0
0
0
17
0
9
0
0
% T
% Val:
9
9
0
59
0
0
9
9
0
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _