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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDN1
All Species:
18.18
Human Site:
S599
Identified Species:
50
UniProt:
Q9NU22
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NU22
NP_055426.1
5596
632820
S599
K
M
A
E
V
I
G
S
K
L
N
I
S
R
K
Chimpanzee
Pan troglodytes
XP_518639
5596
633075
S599
K
M
A
E
V
I
G
S
K
L
N
I
S
R
K
Rhesus Macaque
Macaca mulatta
XP_001091687
4067
460064
Dog
Lupus familis
XP_532232
5590
632716
S599
K
M
A
E
I
I
G
S
K
L
N
I
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074861
5582
629565
S596
R
M
A
E
V
I
G
S
R
L
N
I
S
K
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507898
5508
618389
Q508
K
Q
A
E
F
F
C
Q
L
Y
K
P
E
I
V
Chicken
Gallus gallus
XP_419835
5579
633222
S597
K
M
A
K
V
I
G
S
K
L
N
I
S
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097279
5547
633813
A649
T
L
I
T
S
I
G
A
K
L
G
I
I
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12019
4910
559289
D486
N
L
I
P
K
L
I
D
S
Y
K
N
V
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
70.6
89.4
N.A.
82.2
N.A.
N.A.
70.5
68.4
N.A.
N.A.
N.A.
32.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
71.5
93.8
N.A.
89.7
N.A.
N.A.
82.1
82.1
N.A.
N.A.
N.A.
51.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
80
N.A.
N.A.
20
86.6
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
N.A.
N.A.
20
100
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
56
0
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
67
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
12
67
12
0
0
0
0
67
12
12
0
% I
% Lys:
56
0
0
12
12
0
0
0
56
0
23
0
0
45
56
% K
% Leu:
0
23
0
0
0
12
0
0
12
67
0
0
0
0
0
% L
% Met:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
56
12
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
0
0
0
0
34
0
% R
% Ser:
0
0
0
0
12
0
0
56
12
0
0
0
56
0
23
% S
% Thr:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
45
0
0
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _