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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXD4L1 All Species: 5.15
Human Site: S350 Identified Species: 11.33
UniProt: Q9NU39 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NU39 NP_036316.1 408 43610 S350 S L S P T A W S Y C P L L Q R
Chimpanzee Pan troglodytes NP_001009014 413 45421 A347 V C P R P R G A T A T C S S D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_032048 444 48029 S346 S P S F A P W S Y C H L L Q H
Rat Rattus norvegicus XP_001078871 432 47072 S346 S P P F A P W S Y C H L L Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516678 728 77542 H497 P A A P S L L H V S A A A A A
Chicken Gallus gallus NP_990282 394 40977 F339 S A P S A Q T F L R P P V T V
Frog Xenopus laevis NP_001079026 371 40000 R318 A A P H T F L R P P V T V Q S
Zebra Danio Brachydanio rerio NP_571365 371 40457 F315 S L R A I Q T F L R P P V T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523814 456 49036 V370 S C E D K I D V E S G N E Q E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496411 333 37274 F281 V P N M P A F F I P Q N I D S
Sea Urchin Strong. purpuratus XP_001188749 401 43606 A349 H P H P S L L A M N P T L A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.9 N.A. N.A. N.A. 56.9 57.4 N.A. 32.1 42.1 38.7 38.9 N.A. 30.4 N.A. 32.1 34.8
Protein Similarity: 100 75.3 N.A. N.A. N.A. 63.5 65 N.A. 38.3 52.7 50.9 49 N.A. 45.3 N.A. 46.5 45.5
P-Site Identity: 100 0 N.A. N.A. N.A. 60 53.3 N.A. 6.6 13.3 13.3 20 N.A. 13.3 N.A. 6.6 20
P-Site Similarity: 100 6.6 N.A. N.A. N.A. 60 53.3 N.A. 20 20 26.6 26.6 N.A. 13.3 N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 28 10 10 28 19 0 19 0 10 10 10 10 19 10 % A
% Cys: 0 19 0 0 0 0 0 0 0 28 0 10 0 0 0 % C
% Asp: 0 0 0 10 0 0 10 0 0 0 0 0 0 10 10 % D
% Glu: 0 0 10 0 0 0 0 0 10 0 0 0 10 0 10 % E
% Phe: 0 0 0 19 0 10 10 28 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % G
% His: 10 0 10 10 0 0 0 10 0 0 19 0 0 0 19 % H
% Ile: 0 0 0 0 10 10 0 0 10 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 19 0 0 0 19 28 0 19 0 0 28 37 0 10 % L
% Met: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 10 0 19 0 0 0 % N
% Pro: 10 37 37 28 19 19 0 0 10 19 37 19 0 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 0 0 10 0 0 46 0 % Q
% Arg: 0 0 10 10 0 10 0 10 0 19 0 0 0 0 10 % R
% Ser: 55 0 19 10 19 0 0 28 0 19 0 0 10 10 19 % S
% Thr: 0 0 0 0 19 0 19 0 10 0 10 19 0 19 0 % T
% Val: 19 0 0 0 0 0 0 10 10 0 10 0 28 0 19 % V
% Trp: 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _