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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSS1
All Species:
18.48
Human Site:
S654
Identified Species:
45.19
UniProt:
Q9NUB1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUB1
NP_115890.2
689
74857
S654
L
L
R
K
I
I
T
S
E
A
Q
E
L
G
D
Chimpanzee
Pan troglodytes
XP_001149014
699
75890
S653
L
L
R
K
I
I
T
S
E
A
Q
E
L
G
D
Rhesus Macaque
Macaca mulatta
XP_001099300
688
74713
S653
L
L
R
K
I
I
T
S
E
A
Q
E
L
G
D
Dog
Lupus familis
XP_534200
628
68196
Q596
K
I
I
T
G
R
T
Q
D
L
G
D
I
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB1
682
74605
S647
L
L
R
K
I
I
T
S
R
G
Q
D
L
G
D
Rat
Rattus norvegicus
NP_001099994
682
74873
S647
L
L
R
K
I
I
T
S
R
G
Q
D
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507198
478
52602
R447
V
I
N
I
S
G
H
R
L
G
T
A
E
V
E
Chicken
Gallus gallus
XP_415011
602
67099
S571
K
V
V
T
E
Q
S
S
N
M
G
D
V
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074125
693
76670
Q659
I
L
R
K
V
A
V
Q
D
T
S
N
L
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790649
655
73166
A624
R
V
L
R
K
V
S
A
D
Q
S
D
E
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.2
74.7
N.A.
86.9
85.9
N.A.
59
68.3
N.A.
68.6
N.A.
N.A.
N.A.
N.A.
56
Protein Similarity:
100
98
98.5
80.6
N.A.
92.5
92.1
N.A.
64.3
77.7
N.A.
80.5
N.A.
N.A.
N.A.
N.A.
69.3
P-Site Identity:
100
100
100
6.6
N.A.
80
80
N.A.
0
6.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
86.6
N.A.
20
33.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
30
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
30
0
0
50
0
0
60
% D
% Glu:
0
0
0
0
10
0
0
0
30
0
0
30
20
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
30
20
0
0
60
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
20
10
10
50
50
0
0
0
0
0
0
10
0
0
% I
% Lys:
20
0
0
60
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
50
60
10
0
0
0
0
0
10
10
0
0
60
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
20
0
10
50
0
0
0
0
% Q
% Arg:
10
0
60
10
0
10
0
10
20
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
20
60
0
0
20
0
0
0
0
% S
% Thr:
0
0
0
20
0
0
60
0
0
10
10
0
0
20
20
% T
% Val:
10
20
10
0
10
10
10
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _