KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM14B
All Species:
39.09
Human Site:
Y57
Identified Species:
71.67
UniProt:
Q9NUH8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUH8
NP_001121183.1
114
12078
Y57
G
L
G
A
Y
Q
L
Y
Q
D
P
R
N
V
W
Chimpanzee
Pan troglodytes
XP_001167565
114
12030
Y57
G
L
G
A
Y
Q
L
Y
Q
D
P
R
N
V
W
Rhesus Macaque
Macaca mulatta
XP_001094148
114
12006
S57
G
L
G
S
Y
Q
M
S
Q
D
P
R
N
V
W
Dog
Lupus familis
XP_535885
114
11732
S57
G
L
G
A
Y
Q
L
S
Q
D
P
R
N
I
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQN6
114
11623
S57
G
L
G
A
Y
Q
L
S
Q
D
P
R
N
V
W
Rat
Rattus norvegicus
Q924P2
115
11757
S57
G
L
G
A
Y
Q
L
S
Q
D
P
R
N
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514626
142
14235
S84
G
L
G
A
Y
Q
L
S
Q
D
P
K
N
V
W
Chicken
Gallus gallus
XP_418940
107
11066
S49
G
L
G
A
Y
Q
L
S
Q
N
P
S
N
V
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q0P436
107
10663
S49
G
F
G
A
Y
Q
T
S
Q
D
P
G
N
I
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K0
112
11563
S49
G
Y
G
A
H
L
N
S
Q
D
T
P
R
P
L
Honey Bee
Apis mellifera
XP_001120404
113
11638
S49
G
Y
G
A
Y
Q
T
S
Q
D
P
T
N
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795741
101
10475
S45
A
M
A
G
Y
G
A
S
L
T
S
K
N
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47131
105
11232
H47
G
I
A
G
Y
L
L
H
M
N
R
D
G
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
90.3
71
N.A.
71
68.6
N.A.
53.5
59.6
N.A.
56.1
N.A.
41.2
43.8
N.A.
44.7
Protein Similarity:
100
99.1
93.8
78.9
N.A.
78.9
76.5
N.A.
60.5
65.7
N.A.
64.9
N.A.
52.6
57
N.A.
57.8
P-Site Identity:
100
100
80
86.6
N.A.
93.3
93.3
N.A.
86.6
80
N.A.
66.6
N.A.
33.3
60
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
N.A.
73.3
N.A.
40
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
77
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
77
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
93
0
85
16
0
8
0
0
0
0
0
8
8
8
8
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
24
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% K
% Leu:
0
62
0
0
0
16
62
0
8
0
0
0
0
0
16
% L
% Met:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
16
0
0
85
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
77
8
0
16
0
% P
% Gln:
0
0
0
0
0
77
0
0
85
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
47
8
0
0
% R
% Ser:
0
0
0
8
0
0
0
77
0
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
0
0
8
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% W
% Tyr:
0
16
0
0
93
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _