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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC76 All Species: 22.73
Human Site: S449 Identified Species: 35.71
UniProt: Q9NUP7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUP7 NP_061956.2 481 54247 S449 Y L Q Q K G F S P A L Q Y Y T
Chimpanzee Pan troglodytes XP_001160498 481 54221 S449 Y L Q Q K G F S P A L Q Y Y T
Rhesus Macaque Macaca mulatta XP_001106928 481 54041 S449 Y L Q Q K G F S P A L Q Y Y T
Dog Lupus familis XP_537056 468 52622 S436 Y L Q Q K G F S P A L Q Y Y T
Cat Felis silvestris
Mouse Mus musculus Q8BYH3 481 54242 S448 Y L Q Q K G F S P A L Q Y Y T
Rat Rattus norvegicus NP_001029074 495 55621 S448 Y L Q Q K G F S P A L Q Y Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512523 439 49523 D407 Y L Q Q K G Y D A E L Q Y Y T
Chicken Gallus gallus XP_422313 472 52931 Q441 H G R I R Y L Q H R G Y K A A
Frog Xenopus laevis NP_001085344 467 52459 R434 K L L I D Y G R V D Y L Q R M
Zebra Danio Brachydanio rerio NP_001014331 457 51269 L426 D H G R V H Y L Q K K G F K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649646 441 50395 Q408 H L R S H G Y Q A E L K F Y V
Honey Bee Apis mellifera XP_001120526 382 43417 L351 N W G R L E Y L K N V G F Q S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001140546 453 49752 D416 S M C K D I I D T G R L L W L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192097 453 51089 H422 R M K W V K K H G L N S K L V
Baker's Yeast Sacchar. cerevisiae Q12383 476 54077 V443 V I D E G R L V Y V K E K F T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.9 88.9 N.A. 84.8 82.6 N.A. 67.5 63.4 56.7 56.5 N.A. 31.1 30.5 N.A. N.A.
Protein Similarity: 100 99.7 98.7 91.6 N.A. 91.6 89.2 N.A. 75.4 78.1 72.7 71.3 N.A. 52.8 49 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 0 6.6 6.6 N.A. 26.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 20 6.6 26.6 N.A. 60 33.3 N.A. N.A.
Percent
Protein Identity: N.A. 24.3 N.A. 25.5 23.4 N.A.
Protein Similarity: N.A. 42.2 N.A. 44 44.2 N.A.
P-Site Identity: N.A. 0 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 14 40 0 0 0 7 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 14 0 0 14 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 7 0 0 0 14 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 40 0 0 0 0 0 20 7 0 % F
% Gly: 0 7 14 0 7 54 7 0 7 7 7 14 0 0 0 % G
% His: 14 7 0 0 7 7 0 7 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 14 0 7 7 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 7 7 47 7 7 0 7 7 14 7 20 7 0 % K
% Leu: 0 60 7 0 7 0 14 14 0 7 54 14 7 7 7 % L
% Met: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 7 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % P
% Gln: 0 0 47 47 0 0 0 14 7 0 0 47 7 7 0 % Q
% Arg: 7 0 14 14 7 7 0 7 0 7 7 0 0 7 0 % R
% Ser: 7 0 0 7 0 0 0 40 0 0 0 7 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 60 % T
% Val: 7 0 0 0 14 0 0 7 7 7 7 0 0 0 14 % V
% Trp: 0 7 0 7 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 47 0 0 0 0 14 27 0 7 0 7 7 47 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _