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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB8 All Species: 35.15
Human Site: S291 Identified Species: 70.3
UniProt: Q9NUT2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUT2 NP_009119.2 735 79989 S291 L V S L S M L S T R L T L L L
Chimpanzee Pan troglodytes XP_519524 713 77440 S291 L V S L S M L S T R L T L L L
Rhesus Macaque Macaca mulatta XP_001101229 735 79938 S291 L V S L S M L S T R L T L L L
Dog Lupus familis XP_539916 713 77840 S274 L V S L S M L S T R L T L L L
Cat Felis silvestris
Mouse Mus musculus Q9CXJ4 717 77981 S273 L V S L S M L S P R L T L M L
Rat Rattus norvegicus Q5RKI8 714 77752 S273 L M T L S I L S P R L T L M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q56A55 714 77317 S289 F V S L Y F I S P K L T G L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572810 761 83562 S281 S I S L F M I S P H M A A I A
Honey Bee Apis mellifera XP_624810 657 72388 S233 I V S V I G I S P Q L A A A T
Nematode Worm Caenorhab. elegans NP_490828 668 73334 S244 I G S L Y F L S P T M T M Y T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 V227 T L L A L V V V P V I S V A V
Baker's Yeast Sacchar. cerevisiae P33311 773 85119 S267 V G M M C S L S P Q L S I L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 95.7 85.4 N.A. 82 80.6 N.A. N.A. N.A. N.A. 57.5 N.A. 46.3 41.9 44.4 N.A.
Protein Similarity: 100 94.2 97.4 89.8 N.A. 88 87.6 N.A. N.A. N.A. N.A. 70.7 N.A. 62.2 63.5 60.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 66.6 N.A. N.A. N.A. N.A. 46.6 N.A. 26.6 26.6 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 60 N.A. 53.3 53.3 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.5 29.6 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 48.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 0 17 17 17 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 9 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 0 0 0 9 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 17 9 0 0 9 9 25 0 0 0 9 0 9 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 50 9 9 75 9 0 67 0 0 0 75 0 50 50 59 % L
% Met: 0 9 9 9 0 50 0 0 0 0 17 0 9 17 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % R
% Ser: 9 0 75 0 50 9 0 92 0 0 0 17 0 0 0 % S
% Thr: 9 0 9 0 0 0 0 0 34 9 0 67 0 0 25 % T
% Val: 9 59 0 9 0 9 9 9 0 9 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 17 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _