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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB8 All Species: 37.88
Human Site: S320 Identified Species: 75.76
UniProt: Q9NUT2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUT2 NP_009119.2 735 79989 S320 G S G L R K L S R Q C Q E Q I
Chimpanzee Pan troglodytes XP_519524 713 77440 S320 G S G L R K L S R Q C Q E Q I
Rhesus Macaque Macaca mulatta XP_001101229 735 79938 S320 G S G L R K L S R Q C Q E Q I
Dog Lupus familis XP_539916 713 77840 S303 G S A L R K L S R Q C Q E Q V
Cat Felis silvestris
Mouse Mus musculus Q9CXJ4 717 77981 S302 G S G L R K L S R Q C Q E Q I
Rat Rattus norvegicus Q5RKI8 714 77752 S302 G S G L R K L S R Q C Q E Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q56A55 714 77317 S318 G S F L R K L S R K A Q E Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572810 761 83562 S310 G K K L R S L S K S S Q A Q A
Honey Bee Apis mellifera XP_624810 657 72388 S262 G K G L R K L S M E A Q N Q L
Nematode Worm Caenorhab. elegans NP_490828 668 73334 S273 G A G L R Q L S R R A Q G Q S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 A256 Q A A A A V A A S I A E E S F
Baker's Yeast Sacchar. cerevisiae P33311 773 85119 S296 G K Q I R N T S K D L Q E A T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 95.7 85.4 N.A. 82 80.6 N.A. N.A. N.A. N.A. 57.5 N.A. 46.3 41.9 44.4 N.A.
Protein Similarity: 100 94.2 97.4 89.8 N.A. 88 87.6 N.A. N.A. N.A. N.A. 70.7 N.A. 62.2 63.5 60.4 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. N.A. N.A. N.A. 73.3 N.A. 46.6 60 60 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. N.A. N.A. 86.6 N.A. 53.3 73.3 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.5 29.6 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 48.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 17 9 9 0 9 9 0 0 34 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 9 75 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 92 0 59 0 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 42 % I
% Lys: 0 25 9 0 0 67 0 0 17 9 0 0 0 0 0 % K
% Leu: 0 0 0 84 0 0 84 0 0 0 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 0 9 0 0 0 50 0 92 0 84 0 % Q
% Arg: 0 0 0 0 92 0 0 0 67 9 0 0 0 0 0 % R
% Ser: 0 59 0 0 0 9 0 92 9 9 9 0 0 9 9 % S
% Thr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _