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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB8 All Species: 19.7
Human Site: S57 Identified Species: 39.39
UniProt: Q9NUT2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUT2 NP_009119.2 735 79989 S57 Y S D G Y R S S S L L R A V A
Chimpanzee Pan troglodytes XP_519524 713 77440 S57 Y S D G Y C S S S L L R A V A
Rhesus Macaque Macaca mulatta XP_001101229 735 79938 S57 Y S D G H R S S T L L R A V A
Dog Lupus familis XP_539916 713 77840 S40 S S N G H H A S Y L L R A V A
Cat Felis silvestris
Mouse Mus musculus Q9CXJ4 717 77981 S40 S S D D R L S S H L L R T V A
Rat Rattus norvegicus Q5RKI8 714 77752 S40 S S D D Q F S S C L L R A V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q56A55 714 77317 T52 S S S Q I P S T Q L T V G V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572810 761 83562 P51 G T N A P Q P P A I P P T N A
Honey Bee Apis mellifera XP_624810 657 72388 V39 N S S I K E V V I N N T S K S
Nematode Worm Caenorhab. elegans NP_490828 668 73334 I38 K P I S R T T I L K T W R I C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 A35 N Q E D K P K A N G S E N G L
Baker's Yeast Sacchar. cerevisiae P33311 773 85119 P53 S R L C L R S P A V G K S L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 95.7 85.4 N.A. 82 80.6 N.A. N.A. N.A. N.A. 57.5 N.A. 46.3 41.9 44.4 N.A.
Protein Similarity: 100 94.2 97.4 89.8 N.A. 88 87.6 N.A. N.A. N.A. N.A. 70.7 N.A. 62.2 63.5 60.4 N.A.
P-Site Identity: 100 93.3 86.6 60 N.A. 60 66.6 N.A. N.A. N.A. N.A. 26.6 N.A. 6.6 6.6 0 N.A.
P-Site Similarity: 100 93.3 100 80 N.A. 60 66.6 N.A. N.A. N.A. N.A. 33.3 N.A. 40 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.5 29.6 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 48.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 9 9 17 0 0 0 42 0 59 % A
% Cys: 0 0 0 9 0 9 0 0 9 0 0 0 0 0 9 % C
% Asp: 0 0 42 25 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 9 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 34 0 0 0 0 0 9 9 0 9 9 0 % G
% His: 0 0 0 0 17 9 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 9 0 0 9 9 9 0 0 0 9 9 % I
% Lys: 9 0 0 0 17 0 9 0 0 9 0 9 0 9 0 % K
% Leu: 0 0 9 0 9 9 0 0 9 59 50 0 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 17 0 0 0 0 0 9 9 9 0 9 9 0 % N
% Pro: 0 9 0 0 9 17 9 17 0 0 9 9 0 0 9 % P
% Gln: 0 9 0 9 9 9 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 17 25 0 0 0 0 0 50 9 0 0 % R
% Ser: 42 67 17 9 0 0 59 50 17 0 9 0 17 0 9 % S
% Thr: 0 9 0 0 0 9 9 9 9 0 17 9 17 0 0 % T
% Val: 0 0 0 0 0 0 9 9 0 9 0 9 0 59 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 25 0 0 0 17 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _