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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB8 All Species: 4.24
Human Site: Y54 Identified Species: 8.48
UniProt: Q9NUT2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUT2 NP_009119.2 735 79989 Y54 E G E Y S D G Y R S S S L L R
Chimpanzee Pan troglodytes XP_519524 713 77440 Y54 E G E Y S D G Y C S S S L L R
Rhesus Macaque Macaca mulatta XP_001101229 735 79938 H54 E G E Y S D G H R S S T L L R
Dog Lupus familis XP_539916 713 77840 H37 A V R S S N G H H A S Y L L R
Cat Felis silvestris
Mouse Mus musculus Q9CXJ4 717 77981 R37 A A R S S D D R L S S H L L R
Rat Rattus norvegicus Q5RKI8 714 77752 Q37 A A R S S D D Q F S S C L L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q56A55 714 77317 I49 A P W S S S Q I P S T Q L T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572810 761 83562 P48 H L R G T N A P Q P P A I P P
Honey Bee Apis mellifera XP_624810 657 72388 K36 K K F N S S I K E V V I N N T
Nematode Worm Caenorhab. elegans NP_490828 668 73334 R35 W L H K P I S R T T I L K T W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 K32 L L Q N Q E D K P K A N G S E
Baker's Yeast Sacchar. cerevisiae P33311 773 85119 L50 I P L S R L C L R S P A V G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 95.7 85.4 N.A. 82 80.6 N.A. N.A. N.A. N.A. 57.5 N.A. 46.3 41.9 44.4 N.A.
Protein Similarity: 100 94.2 97.4 89.8 N.A. 88 87.6 N.A. N.A. N.A. N.A. 70.7 N.A. 62.2 63.5 60.4 N.A.
P-Site Identity: 100 93.3 86.6 40 N.A. 46.6 46.6 N.A. N.A. N.A. N.A. 20 N.A. 0 6.6 0 N.A.
P-Site Similarity: 100 93.3 100 60 N.A. 46.6 46.6 N.A. N.A. N.A. N.A. 26.6 N.A. 33.3 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.5 29.6 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 48.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 17 0 0 0 0 9 0 0 9 9 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 9 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 42 25 0 0 0 0 0 0 0 0 % D
% Glu: 25 0 25 0 0 9 0 0 9 0 0 0 0 0 9 % E
% Phe: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 25 0 9 0 0 34 0 0 0 0 0 9 9 0 % G
% His: 9 0 9 0 0 0 0 17 9 0 0 9 0 0 0 % H
% Ile: 9 0 0 0 0 9 9 9 0 0 9 9 9 0 0 % I
% Lys: 9 9 0 9 0 0 0 17 0 9 0 0 9 0 9 % K
% Leu: 9 25 9 0 0 9 0 9 9 0 0 9 59 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 0 17 0 0 0 0 0 9 9 9 0 % N
% Pro: 0 17 0 0 9 0 0 9 17 9 17 0 0 9 9 % P
% Gln: 0 0 9 0 9 0 9 9 9 0 0 9 0 0 0 % Q
% Arg: 0 0 34 0 9 0 0 17 25 0 0 0 0 0 50 % R
% Ser: 0 0 0 42 67 17 9 0 0 59 50 17 0 9 0 % S
% Thr: 0 0 0 0 9 0 0 0 9 9 9 9 0 17 9 % T
% Val: 0 9 0 0 0 0 0 0 0 9 9 0 9 0 9 % V
% Trp: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 25 0 0 0 17 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _