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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTLC3
All Species:
13.03
Human Site:
S24
Identified Species:
23.89
UniProt:
Q9NUV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUV7
NP_060797.2
552
62049
S24
H
K
K
Q
S
N
G
S
Q
S
R
N
C
T
K
Chimpanzee
Pan troglodytes
XP_001135070
552
61957
S24
H
K
K
Q
S
N
G
S
Q
S
R
N
C
T
K
Rhesus Macaque
Macaca mulatta
XP_001082737
552
62893
L24
H
K
K
Q
S
N
G
L
Q
S
R
N
C
T
K
Dog
Lupus familis
XP_542889
552
61959
S24
H
E
K
Q
S
D
G
S
P
S
G
N
C
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG54
563
63467
R24
P
K
T
Q
Q
G
K
R
Q
S
T
G
C
V
K
Rat
Rattus norvegicus
NP_001099987
563
63673
R24
P
K
T
Q
P
G
K
R
Q
S
T
D
C
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514082
550
62189
S22
H
R
K
Q
S
N
G
S
R
G
G
P
C
K
R
Chicken
Gallus gallus
XP_001231526
517
58495
L11
N
G
V
T
N
G
T
L
C
K
K
T
F
I
E
Frog
Xenopus laevis
NP_001089928
550
61746
L20
H
S
G
H
R
E
P
L
K
N
G
L
H
K
K
Zebra Danio
Brachydanio rerio
NP_001003562
553
62638
T27
Q
K
Q
T
E
N
Y
T
L
K
N
G
Y
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784261
549
60922
A25
L
R
Q
N
G
S
V
A
Y
T
N
G
H
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40970
561
63092
D20
C
E
P
E
E
L
P
D
D
I
Q
K
E
N
E
Red Bread Mold
Neurospora crassa
Q7RVY5
629
67428
A30
L
R
A
M
T
T
A
A
R
P
A
A
S
P
C
Conservation
Percent
Protein Identity:
100
99.6
91.4
90
N.A.
69.6
70.5
N.A.
83.1
73.3
73.3
69.6
N.A.
N.A.
N.A.
N.A.
54.8
Protein Similarity:
100
99.8
94.5
95.8
N.A.
81.7
82
N.A.
91.8
83.8
84.5
83.1
N.A.
N.A.
N.A.
N.A.
71.3
P-Site Identity:
100
100
93.3
66.6
N.A.
40
40
N.A.
53.3
0
13.3
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
40
46.6
N.A.
73.3
26.6
26.6
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
41.5
24.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
60.6
40.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
16
0
0
8
8
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
54
0
8
% C
% Asp:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
0
% D
% Glu:
0
16
0
8
16
8
0
0
0
0
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
8
0
8
24
39
0
0
8
24
24
0
0
0
% G
% His:
47
0
0
8
0
0
0
0
0
0
0
0
16
16
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
47
39
0
0
0
16
0
8
16
8
8
0
16
70
% K
% Leu:
16
0
0
0
0
8
0
24
8
0
0
8
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
39
0
0
0
8
16
31
0
8
0
% N
% Pro:
16
0
8
0
8
0
16
0
8
8
0
8
0
8
0
% P
% Gln:
8
0
16
54
8
0
0
0
39
0
8
0
0
0
0
% Q
% Arg:
0
24
0
0
8
0
0
16
16
0
24
0
0
0
8
% R
% Ser:
0
8
0
0
39
8
0
31
0
47
0
0
8
0
0
% S
% Thr:
0
0
16
16
8
8
8
8
0
8
16
8
0
24
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _