KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TDP1
All Species:
12.73
Human Site:
S81
Identified Species:
23.33
UniProt:
Q9NUW8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUW8
NP_001008744.1
608
68420
S81
P
K
R
Q
K
S
G
S
Q
E
D
L
G
W
C
Chimpanzee
Pan troglodytes
XP_510113
677
75678
S150
P
K
R
Q
K
S
G
S
Q
E
D
L
G
W
C
Rhesus Macaque
Macaca mulatta
XP_001089545
603
68022
L81
K
S
G
S
Q
E
D
L
G
W
C
L
S
S
S
Dog
Lupus familis
XP_547950
609
68466
G81
S
P
K
R
Q
R
S
G
S
Q
E
D
L
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ37
609
68671
S81
H
K
K
Q
K
S
D
S
P
E
G
L
G
W
C
Rat
Rattus norvegicus
Q4G056
609
68614
S81
H
K
K
Q
K
M
D
S
P
E
G
L
G
W
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421313
606
67931
R81
T
P
P
A
E
K
Q
R
P
G
Q
E
G
L
G
Frog
Xenopus laevis
NP_001087094
597
67899
T81
I
P
A
K
K
I
K
T
E
S
E
V
S
G
W
Zebra Danio
Brachydanio rerio
XP_700174
615
70098
H81
S
E
A
R
K
S
A
H
V
N
Q
A
N
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQM4
580
64175
V81
S
S
S
S
K
P
A
V
T
A
P
V
A
S
G
Honey Bee
Apis mellifera
XP_392205
692
79662
V118
S
Q
D
L
K
D
K
V
E
K
H
K
Q
I
M
Nematode Worm
Caenorhab. elegans
Q9TXV7
451
51040
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169273
665
74475
A89
G
Q
R
R
K
V
C
A
K
E
T
A
K
I
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
96.5
86.8
N.A.
81.2
81.9
N.A.
N.A.
69.7
66.1
54.1
N.A.
32.4
30
29.1
N.A.
Protein Similarity:
100
87.1
98.1
92.2
N.A.
88.5
88.5
N.A.
N.A.
80.9
79.4
69.9
N.A.
50
45.6
42.9
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
66.6
60
N.A.
N.A.
6.6
6.6
13.3
N.A.
6.6
6.6
0
N.A.
P-Site Similarity:
100
100
13.3
33.3
N.A.
73.3
66.6
N.A.
N.A.
13.3
40
26.6
N.A.
13.3
26.6
0
N.A.
Percent
Protein Identity:
N.A.
32
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
0
16
8
0
8
0
16
8
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
31
% C
% Asp:
0
0
8
0
0
8
24
0
0
0
16
8
0
0
0
% D
% Glu:
0
8
0
0
8
8
0
0
16
39
16
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
16
8
8
8
16
0
39
16
16
% G
% His:
16
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% I
% Lys:
8
31
24
8
70
8
16
0
8
8
0
8
8
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
0
39
8
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
16
24
8
0
0
8
0
0
24
0
8
0
0
8
0
% P
% Gln:
0
16
0
31
16
0
8
0
16
8
16
0
8
0
0
% Q
% Arg:
0
0
24
24
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
31
16
8
16
0
31
8
31
8
8
0
0
16
16
8
% S
% Thr:
8
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
16
8
0
0
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
31
16
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _