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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TDP1
All Species:
36.36
Human Site:
T496
Identified Species:
66.67
UniProt:
Q9NUW8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUW8
NP_001008744.1
608
68420
T496
N
A
M
P
H
I
K
T
Y
M
R
P
S
P
D
Chimpanzee
Pan troglodytes
XP_510113
677
75678
T565
N
A
M
P
H
I
K
T
Y
M
R
P
S
P
D
Rhesus Macaque
Macaca mulatta
XP_001089545
603
68022
T491
N
A
M
P
H
I
K
T
Y
M
R
P
S
P
D
Dog
Lupus familis
XP_547950
609
68466
T497
N
A
M
P
H
I
K
T
Y
M
R
S
S
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ37
609
68671
T497
N
A
M
P
H
I
K
T
Y
M
R
P
S
P
D
Rat
Rattus norvegicus
Q4G056
609
68614
T497
N
A
M
P
H
I
K
T
Y
M
R
P
S
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421313
606
67931
T492
H
A
M
P
H
I
K
T
Y
M
R
P
S
H
D
Frog
Xenopus laevis
NP_001087094
597
67899
T485
Q
A
I
P
H
I
K
T
Y
M
R
F
S
P
D
Zebra Danio
Brachydanio rerio
XP_700174
615
70098
T504
N
A
M
P
H
I
K
T
Y
M
R
I
S
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQM4
580
64175
S469
Y
L
Q
Q
W
K
S
S
D
R
F
R
S
R
A
Honey Bee
Apis mellifera
XP_392205
692
79662
S565
G
S
C
C
L
P
Y
S
L
Q
T
H
S
K
Q
Nematode Worm
Caenorhab. elegans
Q9TXV7
451
51040
M340
Q
K
W
L
Q
G
N
M
C
K
W
R
S
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169273
665
74475
I529
R
C
R
A
M
P
H
I
K
T
F
T
R
Y
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
96.5
86.8
N.A.
81.2
81.9
N.A.
N.A.
69.7
66.1
54.1
N.A.
32.4
30
29.1
N.A.
Protein Similarity:
100
87.1
98.1
92.2
N.A.
88.5
88.5
N.A.
N.A.
80.9
79.4
69.9
N.A.
50
45.6
42.9
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
80
93.3
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
86.6
93.3
N.A.
13.3
20
6.6
N.A.
Percent
Protein Identity:
N.A.
32
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
8
0
0
0
0
0
0
0
0
0
0
16
% A
% Cys:
0
8
8
8
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
70
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
70
0
8
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
8
0
0
70
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
0
0
8
70
0
8
8
0
0
0
8
0
% K
% Leu:
0
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
62
0
8
0
0
8
0
70
0
0
0
0
0
% M
% Asn:
54
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
70
0
16
0
0
0
0
0
47
0
62
0
% P
% Gln:
16
0
8
8
8
0
0
0
0
8
0
0
0
0
8
% Q
% Arg:
8
0
8
0
0
0
0
0
0
8
70
16
8
8
0
% R
% Ser:
0
8
0
0
0
0
8
16
0
0
0
8
93
0
8
% S
% Thr:
0
0
0
0
0
0
0
70
0
8
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
70
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _