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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POT1 All Species: 9.09
Human Site: S309 Identified Species: 22.22
UniProt: Q9NUX5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUX5 NP_001036059.1 634 71442 S309 H S D V I C Q S E P D D S F P
Chimpanzee Pan troglodytes XP_001149671 726 81857 S401 H S D V I C Q S E P D D S F P
Rhesus Macaque Macaca mulatta XP_001087702 634 71467 S309 H S D V I C Q S E P D D S F P
Dog Lupus familis XP_851415 942 104633 H610 Q C S D A I C H S E Q E D S L
Cat Felis silvestris
Mouse Mus musculus Q91WC1 640 70845 C309 T E T S T G I C Q S E N G D S
Rat Rattus norvegicus Q68FS2 406 46271 I106 F E E Q V A S I R Q R L A S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508179 782 87754 P456 Q C L N S I P P V E P D D S L
Chicken Gallus gallus P62597 778 87466 E453 M E S V S S L E L G D T F D S
Frog Xenopus laevis NP_001084422 621 70485 I315 N I A S Q E I I T T L H P Q L
Zebra Danio Brachydanio rerio Q6P0H6 406 46327 I106 F E E Q V A S I R Q H L A T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 98.7 60.1 N.A. 75.1 20.3 N.A. 55.3 49.6 50.4 20 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87 99.2 64.4 N.A. 84.2 35.6 N.A. 66.5 63.5 68.1 35.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 0 0 N.A. 6.6 13.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 20 20 N.A. 6.6 13.3 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 20 0 0 0 0 0 0 20 0 0 % A
% Cys: 0 20 0 0 0 30 10 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 30 10 0 0 0 0 0 0 40 40 20 20 0 % D
% Glu: 0 40 20 0 0 10 0 10 30 20 10 10 0 0 0 % E
% Phe: 20 0 0 0 0 0 0 0 0 0 0 0 10 30 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 10 0 0 10 0 0 % G
% His: 30 0 0 0 0 0 0 10 0 0 10 10 0 0 0 % H
% Ile: 0 10 0 0 30 20 20 30 0 0 0 0 0 0 20 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 10 0 10 0 10 20 0 0 30 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 10 0 30 10 0 10 0 30 % P
% Gln: 20 0 0 20 10 0 30 0 10 20 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 20 0 10 0 0 0 0 % R
% Ser: 0 30 20 20 20 10 20 30 10 10 0 0 30 30 20 % S
% Thr: 10 0 10 0 10 0 0 0 10 10 0 10 0 10 0 % T
% Val: 0 0 0 40 20 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _