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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POT1
All Species:
16.06
Human Site:
T406
Identified Species:
39.26
UniProt:
Q9NUX5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUX5
NP_001036059.1
634
71442
T406
I
I
F
Q
D
G
A
T
K
T
P
D
V
K
L
Chimpanzee
Pan troglodytes
XP_001149671
726
81857
T498
I
I
F
Q
D
G
A
T
K
T
P
D
V
K
L
Rhesus Macaque
Macaca mulatta
XP_001087702
634
71467
T406
I
I
L
Q
D
G
A
T
K
T
P
D
V
K
L
Dog
Lupus familis
XP_851415
942
104633
S714
I
I
L
Q
E
G
A
S
K
T
P
D
T
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WC1
640
70845
T412
K
I
L
Q
D
A
A
T
E
A
P
D
I
K
L
Rat
Rattus norvegicus
Q68FS2
406
46271
V189
Q
L
Q
I
H
Y
K
V
C
Y
A
R
V
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508179
782
87754
A555
L
I
L
R
E
S
A
A
K
S
P
N
S
K
L
Chicken
Gallus gallus
P62597
778
87466
A548
F
I
L
Q
G
C
A
A
T
A
P
N
P
E
L
Frog
Xenopus laevis
NP_001084422
621
70485
A398
N
S
D
Y
D
S
V
A
G
I
Q
S
T
S
W
Zebra Danio
Brachydanio rerio
Q6P0H6
406
46327
V189
Q
L
Q
I
H
Y
K
V
C
Y
A
R
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
98.7
60.1
N.A.
75.1
20.3
N.A.
55.3
49.6
50.4
20
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87
99.2
64.4
N.A.
84.2
35.6
N.A.
66.5
63.5
68.1
35.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
60
6.6
N.A.
40
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
73.3
13.3
N.A.
73.3
46.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
70
30
0
20
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
20
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
50
0
0
0
0
0
0
50
0
0
20
% D
% Glu:
0
0
0
0
20
0
0
0
10
0
0
0
0
10
0
% E
% Phe:
10
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
40
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
70
0
20
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
10
0
0
0
0
0
20
0
50
0
0
0
0
60
0
% K
% Leu:
10
20
50
0
0
0
0
0
0
0
0
0
0
20
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
70
0
10
0
0
% P
% Gln:
20
0
20
60
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
0
% R
% Ser:
0
10
0
0
0
20
0
10
0
10
0
10
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
40
10
40
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
10
20
0
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
10
0
20
0
0
0
20
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _