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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POT1 All Species: 16.67
Human Site: T408 Identified Species: 40.74
UniProt: Q9NUX5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUX5 NP_001036059.1 634 71442 T408 F Q D G A T K T P D V K L Q N
Chimpanzee Pan troglodytes XP_001149671 726 81857 T500 F Q D G A T K T P D V K L Q N
Rhesus Macaque Macaca mulatta XP_001087702 634 71467 T408 L Q D G A T K T P D V K L Q N
Dog Lupus familis XP_851415 942 104633 T716 L Q E G A S K T P D T K L Q N
Cat Felis silvestris
Mouse Mus musculus Q91WC1 640 70845 A414 L Q D A A T E A P D I K L K A
Rat Rattus norvegicus Q68FS2 406 46271 Y191 Q I H Y K V C Y A R V L D Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508179 782 87754 S557 L R E S A A K S P N S K L Q N
Chicken Gallus gallus P62597 778 87466 A550 L Q G C A A T A P N P E L Q S
Frog Xenopus laevis NP_001084422 621 70485 I400 D Y D S V A G I Q S T S W Y Q
Zebra Danio Brachydanio rerio Q6P0H6 406 46327 Y191 Q I H Y K V C Y A R V L D Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 98.7 60.1 N.A. 75.1 20.3 N.A. 55.3 49.6 50.4 20 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87 99.2 64.4 N.A. 84.2 35.6 N.A. 66.5 63.5 68.1 35.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 53.3 6.6 N.A. 46.6 33.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 73.3 6.6 N.A. 73.3 53.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 70 30 0 20 20 0 0 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 20 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 50 0 0 0 0 0 0 50 0 0 20 0 0 % D
% Glu: 0 0 20 0 0 0 10 0 0 0 0 10 0 0 0 % E
% Phe: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 40 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 0 0 0 0 0 10 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 20 0 50 0 0 0 0 60 0 10 0 % K
% Leu: 50 0 0 0 0 0 0 0 0 0 0 20 70 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 0 0 70 0 10 0 0 0 0 % P
% Gln: 20 60 0 0 0 0 0 0 10 0 0 0 0 60 10 % Q
% Arg: 0 10 0 0 0 0 0 0 0 20 0 0 0 0 20 % R
% Ser: 0 0 0 20 0 10 0 10 0 10 10 10 0 0 10 % S
% Thr: 0 0 0 0 0 40 10 40 0 0 20 0 0 0 0 % T
% Val: 0 0 0 0 10 20 0 0 0 0 50 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 10 0 20 0 0 0 20 0 0 0 0 0 30 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _