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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM140
All Species:
11.19
Human Site:
S180
Identified Species:
49.23
UniProt:
Q9NV12
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV12
NP_060765.3
185
20419
S180
L
R
A
E
R
A
E
S
K
L
E
S
C
_
_
Chimpanzee
Pan troglodytes
XP_001143901
185
20291
S180
L
R
A
E
R
A
E
S
K
L
E
S
C
_
_
Rhesus Macaque
Macaca mulatta
XP_001104681
185
20639
S180
L
R
A
Y
R
A
Y
S
E
L
E
S
C
_
_
Dog
Lupus familis
XP_849803
184
20022
S179
P
R
R
A
E
D
K
S
K
L
D
S
C
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGY5
185
20748
N180
P
R
D
K
E
D
K
N
Q
W
E
N
C
_
_
Rat
Rattus norvegicus
Q5M826
184
20478
N179
P
R
D
K
K
D
K
N
H
W
E
N
C
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
81.6
72.9
N.A.
63.2
67
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
89.1
84.8
N.A.
76.2
81
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
76.9
46.1
N.A.
23
23
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
84.6
61.5
N.A.
61.5
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
17
0
50
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% C
% Asp:
0
0
34
0
0
50
0
0
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
34
34
0
34
0
17
0
84
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
34
17
0
50
0
50
0
0
0
0
0
0
% K
% Leu:
50
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
34
0
0
0
34
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% Q
% Arg:
0
100
17
0
50
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
67
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
100
% _