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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMP3 All Species: 28.18
Human Site: S105 Identified Species: 51.67
UniProt: Q9NV31 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV31 NP_060755.1 184 21850 S105 C D F V T A S S F C R R R L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544781 224 25491 A145 C D S V T A S A F C R R R L P
Cat Felis silvestris
Mouse Mus musculus Q921Y2 184 21759 S105 C D S V S A S S F C R R R L P
Rat Rattus norvegicus NP_001101622 184 21641 S105 C D S V S A S S F C R R R L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085060 183 21708 S104 C Q N V S A S S F C R R R L P
Zebra Danio Brachydanio rerio NP_956561 179 20978 A104 A N E V S A S A F C R R R L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611224 181 21285 H104 A A K I S A S H F C R R R L P
Honey Bee Apis mellifera XP_623809 182 21664 S104 T Q K V S A S S F C R R R L P
Nematode Worm Caenorhab. elegans O01513 183 21059 S104 I G K V T G A S F A R R R L P
Sea Urchin Strong. purpuratus XP_794777 181 21526 S103 C D N V S A S S F C R R R L P
Poplar Tree Populus trichocarpa XP_002330956 182 21795 S103 C D R L S V S S F C R R R L S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLF0 197 23142 N105 V L A L T V E N F L E R R L Q
Baker's Yeast Sacchar. cerevisiae P32899 183 21867 S104 L E N K V T V S A I C R R R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 79 N.A. 96.1 96.1 N.A. N.A. N.A. 71.1 62.5 N.A. 56.5 60.3 50 63
Protein Similarity: 100 N.A. N.A. 80.3 N.A. 98.9 98.3 N.A. N.A. N.A. 91.8 86.9 N.A. 77.7 83.6 67.9 85.8
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 80 66.6 N.A. 60 73.3 60 86.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. 86.6 86.6 N.A. 73.3 80 66.6 93.3
Percent
Protein Identity: 56.5 N.A. N.A. 29.4 53.2 N.A.
Protein Similarity: 77.7 N.A. N.A. 48.2 73.9 N.A.
P-Site Identity: 66.6 N.A. N.A. 33.3 20 N.A.
P-Site Similarity: 80 N.A. N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 8 0 0 70 8 16 8 8 0 0 0 0 0 % A
% Cys: 54 0 0 0 0 0 0 0 0 77 8 0 0 0 0 % C
% Asp: 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 8 0 0 0 8 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 93 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 24 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 0 16 0 0 0 0 0 8 0 0 0 93 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 24 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77 % P
% Gln: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 85 100 100 8 0 % R
% Ser: 0 0 24 0 62 0 77 70 0 0 0 0 0 0 8 % S
% Thr: 8 0 0 0 31 8 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 0 70 8 16 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _