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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMP3 All Species: 43.64
Human Site: Y45 Identified Species: 80
UniProt: Q9NV31 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV31 NP_060755.1 184 21850 Y45 R L Q R R E D Y T R Y N Q L S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544781 224 25491 Y85 R L Q R R E D Y T R Y N Q L S
Cat Felis silvestris
Mouse Mus musculus Q921Y2 184 21759 Y45 R L Q R R E E Y T R Y N Q L S
Rat Rattus norvegicus NP_001101622 184 21641 Y45 G L Q R R E E Y T R Y N Q L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085060 183 21708 Y44 H L D K R E D Y T K Y N K L S
Zebra Danio Brachydanio rerio NP_956561 179 20978 Y44 H I E K R E D Y T K Y N K L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611224 181 21285 Y44 H I Q K R E D Y T K Y N K L S
Honey Bee Apis mellifera XP_623809 182 21664 Y44 R I Q K R E D Y T K Y N K L A
Nematode Worm Caenorhab. elegans O01513 183 21059 Y44 Y V K K R E H Y A L Y N T L A
Sea Urchin Strong. purpuratus XP_794777 181 21526 Y43 H I Q K R E D Y T K Y N K L S
Poplar Tree Populus trichocarpa XP_002330956 182 21795 Y43 H I V E R D D Y K K Y S S V C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLF0 197 23142 L44 G L R C K R E L W R V Q Y T L
Baker's Yeast Sacchar. cerevisiae P32899 183 21867 Y44 H I Q N R E D Y H K Y N R I C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 79 N.A. 96.1 96.1 N.A. N.A. N.A. 71.1 62.5 N.A. 56.5 60.3 50 63
Protein Similarity: 100 N.A. N.A. 80.3 N.A. 98.9 98.3 N.A. N.A. N.A. 91.8 86.9 N.A. 77.7 83.6 67.9 85.8
P-Site Identity: 100 N.A. N.A. 100 N.A. 93.3 86.6 N.A. N.A. N.A. 66.6 60 N.A. 66.6 66.6 40 66.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 93.3 N.A. N.A. N.A. 86.6 93.3 N.A. 93.3 100 66.6 93.3
Percent
Protein Identity: 56.5 N.A. N.A. 29.4 53.2 N.A.
Protein Similarity: 77.7 N.A. N.A. 48.2 73.9 N.A.
P-Site Identity: 26.6 N.A. N.A. 13.3 46.6 N.A.
P-Site Similarity: 60 N.A. N.A. 33.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 16 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 16 % C
% Asp: 0 0 8 0 0 8 70 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 8 0 85 24 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 47 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % H
% Ile: 0 47 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 8 47 8 0 0 0 8 54 0 0 39 0 0 % K
% Leu: 0 47 0 0 0 0 0 8 0 8 0 0 0 77 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 85 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 62 0 0 0 0 0 0 0 0 8 31 0 0 % Q
% Arg: 31 0 8 31 93 8 0 0 0 39 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 62 % S
% Thr: 0 0 0 0 0 0 0 0 70 0 0 0 8 8 0 % T
% Val: 0 8 8 0 0 0 0 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 93 0 0 93 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _