KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUDT15
All Species:
20.3
Human Site:
S42
Identified Species:
55.83
UniProt:
Q9NV35
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV35
NP_060753.1
164
18609
S42
K
G
S
V
G
A
G
S
F
Q
L
P
G
G
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG93
170
19558
S41
K
G
S
F
G
A
G
S
F
Q
L
P
G
G
H
Rat
Rattus norvegicus
NP_001099519
170
19666
S41
K
G
S
F
G
A
G
S
F
Q
L
P
G
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514152
265
29238
R143
A
H
S
G
R
L
I
R
V
N
K
R
G
G
N
Chicken
Gallus gallus
XP_417053
245
27301
T123
K
G
P
I
G
A
G
T
Y
Q
L
P
G
G
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001330868
155
17624
T45
K
T
R
V
G
K
G
T
Y
Q
L
P
G
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782891
150
16789
S40
K
R
K
G
S
T
G
S
G
T
F
A
L
P
G
Poplar Tree
Populus trichocarpa
XP_002311425
147
16555
T38
C
S
S
V
G
D
S
T
F
A
L
P
G
G
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CA40
147
16338
L38
I
G
N
S
T
F
A
L
P
G
G
H
L
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
85.8
83.5
N.A.
44.5
46.5
N.A.
53.6
N.A.
N.A.
N.A.
N.A.
54.2
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
90.5
88.8
N.A.
52
53.4
N.A.
71.3
N.A.
N.A.
N.A.
N.A.
68.2
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
20
73.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
26.6
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
37.8
N.A.
N.A.
39.6
N.A.
N.A.
Protein Similarity:
53
N.A.
N.A.
55.4
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
45
12
0
0
12
0
12
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
23
0
12
0
0
45
0
12
0
0
0
12
% F
% Gly:
0
56
0
23
67
0
67
0
12
12
12
0
78
78
12
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
67
% H
% Ile:
12
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
67
0
12
0
0
12
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
12
0
0
67
0
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
12
% N
% Pro:
0
0
12
0
0
0
0
0
12
0
0
67
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
56
0
0
0
0
0
% Q
% Arg:
0
12
12
0
12
0
0
12
0
0
0
12
0
0
0
% R
% Ser:
0
12
56
12
12
0
12
45
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
12
12
0
34
0
12
0
0
0
0
0
% T
% Val:
0
0
0
34
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _