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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF19A
All Species:
13.64
Human Site:
S274
Identified Species:
27.27
UniProt:
Q9NV58
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV58
NP_056250.3
838
90696
S274
A
R
Q
E
R
A
Q
S
L
R
L
R
T
I
R
Chimpanzee
Pan troglodytes
XP_001152318
826
89574
S274
A
R
Q
E
R
A
Q
S
L
R
L
R
T
I
R
Rhesus Macaque
Macaca mulatta
XP_001099161
525
56557
Dog
Lupus familis
XP_856300
831
90301
A266
H
P
N
Q
T
C
D
A
A
R
Q
E
R
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
P50636
840
90614
S274
A
R
Q
E
R
A
Q
S
L
R
L
R
T
I
R
Rat
Rattus norvegicus
NP_001124032
840
90385
S274
A
R
Q
E
R
A
Q
S
L
R
L
R
T
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520758
595
62697
K63
G
K
K
P
W
S
R
K
K
K
I
L
W
Q
L
Chicken
Gallus gallus
XP_418362
790
84997
D259
Q
E
S
G
A
A
A
D
D
I
K
P
C
P
R
Frog
Xenopus laevis
Q08B84
687
74523
R156
Q
H
V
R
A
I
L
R
D
P
L
L
T
R
K
Zebra Danio
Brachydanio rerio
Q1L8L6
701
74925
P170
V
A
L
I
L
D
D
P
N
L
M
E
K
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623728
825
90208
C281
I
A
S
G
C
A
S
C
P
K
L
R
C
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780939
783
83193
K252
S
S
S
Q
D
Q
I
K
Q
C
P
R
C
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
47.1
96.9
N.A.
93.5
92.8
N.A.
56.4
85.5
46.9
46.1
N.A.
N.A.
42.9
N.A.
43.9
Protein Similarity:
100
98.5
53.5
97.7
N.A.
96
95.4
N.A.
59.9
88.9
60.8
58.3
N.A.
N.A.
59.9
N.A.
58.5
P-Site Identity:
100
100
0
6.6
N.A.
100
100
N.A.
0
13.3
13.3
0
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
0
26.6
N.A.
100
100
N.A.
40
13.3
20
6.6
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
17
0
0
17
50
9
9
9
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
9
9
0
9
0
9
0
0
25
0
0
% C
% Asp:
0
0
0
0
9
9
17
9
17
0
0
0
0
0
0
% D
% Glu:
0
9
0
34
0
0
0
0
0
0
0
17
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
9
9
0
0
9
9
0
0
34
0
% I
% Lys:
0
9
9
0
0
0
0
17
9
17
9
0
9
0
9
% K
% Leu:
0
0
9
0
9
0
9
0
34
9
50
17
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
9
9
9
9
9
0
9
0
% P
% Gln:
17
0
34
17
0
9
34
0
9
0
9
0
0
9
9
% Q
% Arg:
0
34
0
9
34
0
9
9
0
42
0
50
9
9
50
% R
% Ser:
9
9
25
0
0
9
9
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
42
9
0
% T
% Val:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _