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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM39A All Species: 5.76
Human Site: S229 Identified Species: 15.83
UniProt: Q9NV64 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV64 NP_060736.1 488 55667 S229 E A V E E S A S T V G G L A K
Chimpanzee Pan troglodytes XP_516665 443 49834 C200 F G V Y V P L C C F H Q D S R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535749 533 60916 S274 Q A V E E S A S T V G G L A K
Cat Felis silvestris
Mouse Mus musculus Q9CYC3 486 55702 V229 V E E A A S N V G S L A R S K
Rat Rattus norvegicus Q5U2V9 497 56772 V229 V E D A A S N V G S L T R S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416562 484 55366 S229 D G A S A V S S L V K P K D F
Frog Xenopus laevis Q0IHF1 488 55531 N229 S L V D E G A N G A G S L V R
Zebra Danio Brachydanio rerio Q6PH58 481 54138 D229 G A L L Q P R D F L T L L R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001197906 526 60794 G232 K E E L L W N G I T M L A P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 N.A. 90.9 N.A. 95 90.7 N.A. N.A. 90.1 84.6 70.9 N.A. N.A. N.A. N.A. 45.6
Protein Similarity: 100 88.5 N.A. 91.3 N.A. 96.9 93.7 N.A. N.A. 93.2 92.2 81.9 N.A. N.A. N.A. N.A. 59.3
P-Site Identity: 100 6.6 N.A. 93.3 N.A. 13.3 13.3 N.A. N.A. 13.3 33.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 20 N.A. 100 N.A. 20 20 N.A. N.A. 26.6 53.3 40 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 12 23 34 0 34 0 0 12 0 12 12 23 12 % A
% Cys: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % C
% Asp: 12 0 12 12 0 0 0 12 0 0 0 0 12 12 0 % D
% Glu: 12 34 23 23 34 0 0 0 0 0 0 0 0 0 12 % E
% Phe: 12 0 0 0 0 0 0 0 12 12 0 0 0 0 12 % F
% Gly: 12 23 0 0 0 12 0 12 34 0 34 23 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 0 0 0 12 0 12 0 45 % K
% Leu: 0 12 12 23 12 0 12 0 12 12 23 23 45 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 34 12 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 23 0 0 0 0 0 12 0 12 0 % P
% Gln: 12 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 23 12 23 % R
% Ser: 12 0 0 12 0 45 12 34 0 23 0 12 0 34 0 % S
% Thr: 0 0 0 0 0 0 0 0 23 12 12 12 0 0 0 % T
% Val: 23 0 45 0 12 12 0 23 0 34 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _