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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM39A
All Species:
10.3
Human Site:
S242
Identified Species:
28.33
UniProt:
Q9NV64
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV64
NP_060736.1
488
55667
S242
A
K
S
K
D
F
L
S
L
L
L
E
S
L
K
Chimpanzee
Pan troglodytes
XP_516665
443
49834
T213
S
R
A
H
L
L
L
T
D
Y
N
Y
V
V
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535749
533
60916
S287
A
K
S
K
D
F
L
S
L
L
L
E
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYC3
486
55702
L242
S
K
D
F
L
S
L
L
L
E
S
L
K
E
Q
Rat
Rattus norvegicus
Q5U2V9
497
56772
L242
S
K
D
F
L
S
L
L
L
E
S
L
K
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416562
484
55366
E242
D
F
L
S
L
L
W
E
S
L
R
E
Q
F
N
Frog
Xenopus laevis
Q0IHF1
488
55531
S242
V
R
P
K
D
F
L
S
L
L
R
E
S
L
R
Zebra Danio
Brachydanio rerio
Q6PH58
481
54138
L242
R
E
N
L
R
Q
Q
L
S
G
T
H
T
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197906
526
60794
H245
P
A
K
H
K
C
S
H
V
P
N
E
I
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
N.A.
90.9
N.A.
95
90.7
N.A.
N.A.
90.1
84.6
70.9
N.A.
N.A.
N.A.
N.A.
45.6
Protein Similarity:
100
88.5
N.A.
91.3
N.A.
96.9
93.7
N.A.
N.A.
93.2
92.2
81.9
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
6.6
N.A.
100
N.A.
20
20
N.A.
N.A.
13.3
66.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
46.6
N.A.
100
N.A.
33.3
33.3
N.A.
N.A.
13.3
80
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
23
0
34
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
12
0
23
0
56
0
23
0
% E
% Phe:
0
12
0
23
0
34
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
23
0
0
0
12
0
0
0
12
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
45
12
34
12
0
0
0
0
0
0
0
23
0
23
% K
% Leu:
0
0
12
12
45
23
67
34
56
45
23
23
0
34
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
23
0
0
0
12
% N
% Pro:
12
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
12
0
0
0
0
0
12
0
45
% Q
% Arg:
12
23
0
0
12
0
0
0
0
0
23
0
0
12
12
% R
% Ser:
34
0
23
12
0
23
12
34
23
0
23
0
34
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
12
0
12
0
12
% T
% Val:
12
0
0
0
0
0
0
0
12
0
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _