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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM39A
All Species:
26.06
Human Site:
S438
Identified Species:
71.67
UniProt:
Q9NV64
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV64
NP_060736.1
488
55667
S438
V
V
F
Y
Q
L
Y
S
L
L
R
S
E
K
W
Chimpanzee
Pan troglodytes
XP_516665
443
49834
G395
R
C
L
Y
R
A
M
G
P
Y
N
V
A
V
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535749
533
60916
S483
V
V
F
Y
Q
L
Y
S
L
L
R
S
E
K
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYC3
486
55702
S436
V
V
F
Y
Q
L
Y
S
L
L
R
S
E
K
W
Rat
Rattus norvegicus
Q5U2V9
497
56772
S436
V
I
I
Y
Q
L
Y
S
L
L
R
S
E
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416562
484
55366
S434
V
V
C
Y
Q
L
Y
S
L
L
R
S
E
K
W
Frog
Xenopus laevis
Q0IHF1
488
55531
S438
L
V
L
Y
Q
L
Y
S
L
L
R
A
E
K
W
Zebra Danio
Brachydanio rerio
Q6PH58
481
54138
S429
V
V
V
Y
Q
L
Y
S
L
L
R
S
E
R
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197906
526
60794
D458
L
G
K
F
M
F
H
D
P
L
R
V
L
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
N.A.
90.9
N.A.
95
90.7
N.A.
N.A.
90.1
84.6
70.9
N.A.
N.A.
N.A.
N.A.
45.6
Protein Similarity:
100
88.5
N.A.
91.3
N.A.
96.9
93.7
N.A.
N.A.
93.2
92.2
81.9
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
86.6
N.A.
N.A.
93.3
80
86.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
12
12
0
0
% A
% Cys:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% E
% Phe:
0
0
34
12
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
0
0
67
0
% K
% Leu:
23
0
23
0
0
78
0
0
78
89
0
0
12
0
12
% L
% Met:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
78
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
12
0
0
0
0
0
89
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
78
0
0
0
67
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
67
67
12
0
0
0
0
0
0
0
0
23
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% W
% Tyr:
0
0
0
89
0
0
78
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _