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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM39A All Species: 26.97
Human Site: T448 Identified Species: 74.17
UniProt: Q9NV64 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV64 NP_060736.1 488 55667 T448 R S E K W N H T L S M A L I L
Chimpanzee Pan troglodytes XP_516665 443 49834 V405 N V A V P S D V S H A R F Y A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535749 533 60916 T493 R S E K W N H T L S M A L I L
Cat Felis silvestris
Mouse Mus musculus Q9CYC3 486 55702 T446 R S E K W N H T L S M A L I L
Rat Rattus norvegicus Q5U2V9 497 56772 T446 R S E K W N H T L S M A L V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416562 484 55366 T444 R S E K W N H T L S M A L I L
Frog Xenopus laevis Q0IHF1 488 55531 T448 R A E K W N H T L S I A L I L
Zebra Danio Brachydanio rerio Q6PH58 481 54138 T439 R S E R W N H T L S L G L I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001197906 526 60794 F405 R V L N L F V F L Q L G V I A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 N.A. 90.9 N.A. 95 90.7 N.A. N.A. 90.1 84.6 70.9 N.A. N.A. N.A. N.A. 45.6
Protein Similarity: 100 88.5 N.A. 91.3 N.A. 96.9 93.7 N.A. N.A. 93.2 92.2 81.9 N.A. N.A. N.A. N.A. 59.3
P-Site Identity: 100 0 N.A. 100 N.A. 100 93.3 N.A. N.A. 100 86.6 80 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 0 0 0 0 0 0 12 67 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 12 0 12 0 0 0 0 12 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % G
% His: 0 0 0 0 0 0 78 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 12 0 0 78 0 % I
% Lys: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 12 0 12 0 0 0 89 0 23 0 78 0 78 % L
% Met: 0 0 0 0 0 0 0 0 0 0 56 0 0 0 0 % M
% Asn: 12 0 0 12 0 78 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % Q
% Arg: 89 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % R
% Ser: 0 67 0 0 0 12 0 0 12 78 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 78 0 0 0 0 0 0 0 % T
% Val: 0 23 0 12 0 0 12 12 0 0 0 0 12 12 0 % V
% Trp: 0 0 0 0 78 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _