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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM39A All Species: 9.7
Human Site: Y215 Identified Species: 26.67
UniProt: Q9NV64 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV64 NP_060736.1 488 55667 Y215 A H L L L T D Y N Y V V Q H E
Chimpanzee Pan troglodytes XP_516665 443 49834 L186 R S H S V L N L L F L G Y P F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535749 533 60916 Y260 A H L L L T D Y N Y M V Q Q Q
Cat Felis silvestris
Mouse Mus musculus Q9CYC3 486 55702 Y215 A H L L L T D Y V V Q H Q A V
Rat Rattus norvegicus Q5U2V9 497 56772 Y215 A H L L L T D Y V V Q H Q A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416562 484 55366 V215 P A D C G Y L V Q D Q M V E D
Frog Xenopus laevis Q0IHF1 488 55531 C215 S Q P L P T D C G Y L V P D S
Zebra Danio Brachydanio rerio Q6PH58 481 54138 A215 P A A D C G F A D A D G A D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001197906 526 60794 A218 M T L F S Q L A P P A K G S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 N.A. 90.9 N.A. 95 90.7 N.A. N.A. 90.1 84.6 70.9 N.A. N.A. N.A. N.A. 45.6
Protein Similarity: 100 88.5 N.A. 91.3 N.A. 96.9 93.7 N.A. N.A. 93.2 92.2 81.9 N.A. N.A. N.A. N.A. 59.3
P-Site Identity: 100 0 N.A. 80 N.A. 60 60 N.A. N.A. 0 33.3 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 26.6 N.A. 93.3 N.A. 60 60 N.A. N.A. 13.3 46.6 6.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 23 12 0 0 0 0 23 0 12 12 0 12 23 0 % A
% Cys: 0 0 0 12 12 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 12 0 0 56 0 12 12 12 0 0 23 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 12 % E
% Phe: 0 0 0 12 0 0 12 0 0 12 0 0 0 0 12 % F
% Gly: 0 0 0 0 12 12 0 0 12 0 0 23 12 0 12 % G
% His: 0 45 12 0 0 0 0 0 0 0 0 23 0 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 12 % K
% Leu: 0 0 56 56 45 12 23 12 12 0 23 0 0 0 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 23 0 0 0 0 0 0 % N
% Pro: 23 0 12 0 12 0 0 0 12 12 0 0 12 12 0 % P
% Gln: 0 12 0 0 0 12 0 0 12 0 34 0 45 12 12 % Q
% Arg: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 12 0 12 12 0 0 0 0 0 0 0 0 12 12 % S
% Thr: 0 12 0 0 0 56 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 12 0 0 12 23 23 12 34 12 0 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 45 0 34 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _