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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
14.55
Human Site:
S186
Identified Species:
29.09
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S186
L
G
N
S
A
Y
A
S
H
F
N
K
V
G
K
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S203
L
G
N
S
A
Y
A
S
H
F
N
K
V
G
K
Dog
Lupus familis
XP_536836
714
81505
S191
L
G
N
S
V
Y
A
S
H
F
N
K
V
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
N186
H
F
N
K
V
S
T
N
V
D
K
W
L
W
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
D195
L
G
N
S
V
Y
V
D
H
Y
N
T
V
G
R
Frog
Xenopus laevis
Q2KHP8
735
84095
T190
L
G
N
S
V
Y
S
T
H
Y
N
T
V
G
K
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
G186
L
G
N
S
V
Y
V
G
H
F
N
T
V
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
D189
L
G
N
S
L
Y
Q
D
H
Y
N
T
V
S
K
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
D117
D
F
S
R
R
L
R
D
L
G
A
K
E
V
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
L171
R
M
I
G
L
G
G
L
E
M
I
P
V
G
E
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
S196
I
K
S
A
L
T
I
S
N
E
T
L
L
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
0
100
93.3
N.A.
6.6
N.A.
N.A.
N.A.
60
66.6
66.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
0
100
93.3
N.A.
20
N.A.
N.A.
N.A.
73.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
17
0
25
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
25
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
0
0
9
0
9
% E
% Phe:
0
17
0
0
0
0
0
0
0
34
0
0
0
0
0
% F
% Gly:
0
59
0
9
0
9
9
9
0
9
0
0
0
50
0
% G
% His:
9
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% I
% Lys:
0
9
0
9
0
0
0
0
0
0
9
34
0
0
50
% K
% Leu:
59
0
0
0
25
9
0
9
9
0
0
9
17
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
67
0
0
0
0
9
9
0
59
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
9
0
9
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
17
59
0
9
9
34
0
0
0
0
0
25
9
% S
% Thr:
0
0
0
0
0
9
9
9
0
0
9
34
0
0
0
% T
% Val:
0
0
0
0
42
0
17
0
9
0
0
0
67
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% W
% Tyr:
0
0
0
0
0
59
0
0
0
25
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _