KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
22.42
Human Site:
S220
Identified Species:
44.85
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S220
G
D
C
D
V
V
K
S
K
H
G
S
I
E
A
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S237
G
D
C
D
V
V
K
S
K
H
G
S
I
E
A
Dog
Lupus familis
XP_536836
714
81505
D219
V
V
A
R
G
E
G
D
C
D
V
V
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
S212
G
D
C
N
A
V
Q
S
K
H
G
S
I
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
S229
G
D
C
N
V
V
Q
S
K
H
G
S
I
E
A
Frog
Xenopus laevis
Q2KHP8
735
84095
S224
G
D
C
N
V
V
K
S
K
H
G
S
I
E
S
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
S220
G
D
C
N
V
V
K
S
R
H
G
S
V
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
E215
R
P
L
L
P
V
G
E
G
N
G
N
V
A
A
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
W143
L
D
G
V
F
E
E
W
S
G
R
L
A
R
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
V197
F
Q
D
W
C
D
G
V
I
R
V
L
K
G
G
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
L239
E
L
T
N
E
P
K
L
L
N
L
D
D
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
0
100
0
N.A.
80
N.A.
N.A.
N.A.
86.6
86.6
73.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
0
100
0
N.A.
93.3
N.A.
N.A.
N.A.
100
100
100
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
0
9
9
50
% A
% Cys:
0
0
50
0
9
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
59
9
17
0
9
0
9
0
9
0
9
9
0
0
% D
% Glu:
9
0
0
0
9
17
9
9
0
0
0
0
0
42
0
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
9
0
9
0
25
0
9
9
59
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
42
0
0
% I
% Lys:
0
0
0
0
0
0
42
0
42
0
0
0
17
0
9
% K
% Leu:
9
9
9
9
0
0
0
9
9
0
9
17
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
42
0
0
0
0
0
17
0
9
0
0
0
% N
% Pro:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
17
0
0
0
0
0
0
9
0
% Q
% Arg:
9
0
0
9
0
0
0
0
9
9
9
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
50
9
0
0
50
0
9
17
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
9
0
9
42
59
0
9
0
0
17
9
17
0
9
% V
% Trp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _