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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
9.7
Human Site:
S296
Identified Species:
19.39
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S296
E
E
P
F
E
S
S
S
E
E
E
F
G
G
E
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S313
E
E
P
F
E
S
S
S
E
E
E
F
G
G
E
Dog
Lupus familis
XP_536836
714
81505
D295
Q
N
L
N
S
V
V
D
V
E
D
L
G
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
E288
C
E
S
S
S
E
D
E
L
G
T
Q
D
Y
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
E305
F
E
T
T
S
E
E
E
A
D
A
E
E
A
G
Frog
Xenopus laevis
Q2KHP8
735
84095
S300
D
D
T
F
E
T
S
S
D
S
E
P
E
E
H
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
S296
S
S
S
D
E
E
S
S
S
E
D
E
K
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
D291
G
G
E
E
K
A
D
D
G
L
D
S
D
Q
E
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
G219
G
E
N
G
K
L
N
G
Q
K
E
M
V
T
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
T273
D
G
K
K
E
M
V
T
P
V
I
R
A
S
L
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
E315
G
D
S
E
S
W
P
E
K
F
C
Y
Q
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
0
100
13.3
N.A.
6.6
N.A.
N.A.
N.A.
6.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
0
100
26.6
N.A.
13.3
N.A.
N.A.
N.A.
13.3
60
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
9
0
9
0
9
17
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
17
17
0
9
0
0
17
17
9
9
25
0
17
0
0
% D
% Glu:
17
42
9
17
42
25
9
25
17
34
34
17
17
9
25
% E
% Phe:
9
0
0
25
0
0
0
0
0
9
0
17
0
0
0
% F
% Gly:
25
17
0
9
0
0
0
9
9
9
0
0
25
17
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
9
9
17
0
0
0
9
9
0
0
9
9
9
% K
% Leu:
0
0
9
0
0
9
0
0
9
9
0
9
0
0
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
9
9
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
0
0
9
0
9
0
0
9
0
0
9
% P
% Gln:
9
0
0
0
0
0
0
0
9
0
0
9
9
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
9
25
9
34
17
34
34
9
9
0
9
0
17
0
% S
% Thr:
0
0
17
9
0
9
0
9
0
0
9
0
0
9
0
% T
% Val:
0
0
0
0
0
9
17
0
9
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _