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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
8.79
Human Site:
S338
Identified Species:
17.58
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S338
K
E
Q
Q
E
E
K
S
G
L
F
R
N
M
G
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S355
K
E
Q
Q
E
E
K
S
G
L
F
R
N
M
G
Dog
Lupus familis
XP_536836
714
81505
R324
E
E
K
S
S
L
V
R
N
T
V
K
N
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
A327
K
S
H
Q
D
G
K
A
A
M
Q
R
N
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
A344
R
E
L
E
D
G
D
A
G
M
S
L
L
G
E
Frog
Xenopus laevis
Q2KHP8
735
84095
T338
K
R
E
H
D
S
N
T
E
L
G
K
S
L
Q
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
Q334
E
E
D
E
E
D
S
Q
R
V
K
Q
N
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
A323
N
K
M
K
N
A
K
A
M
N
G
V
K
L
G
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
I248
G
S
H
S
G
V
K
I
C
R
W
T
K
S
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
S302
K
I
C
R
W
T
K
S
Q
L
R
G
R
G
G
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
L392
E
G
N
G
S
D
E
L
G
D
V
E
D
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
0
100
13.3
N.A.
33.3
N.A.
N.A.
N.A.
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
100
33.3
N.A.
53.3
N.A.
N.A.
N.A.
46.6
53.3
53.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
6.6
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
25
9
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
25
17
9
0
0
9
0
0
9
0
9
% D
% Glu:
25
42
9
17
25
17
9
0
9
0
0
9
0
9
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
9
9
0
9
9
17
0
0
34
0
17
9
0
25
42
% G
% His:
0
0
17
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
0
0
0
0
0
9
0
% I
% Lys:
42
9
9
9
0
0
50
0
0
0
9
17
17
0
0
% K
% Leu:
0
0
9
0
0
9
0
9
0
34
0
9
9
17
0
% L
% Met:
0
0
9
0
0
0
0
0
9
17
0
0
0
17
0
% M
% Asn:
9
0
9
0
9
0
9
0
9
9
0
0
42
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
17
25
0
0
0
9
9
0
9
9
0
0
17
% Q
% Arg:
9
9
0
9
0
0
0
9
9
9
9
25
9
0
0
% R
% Ser:
0
17
0
17
17
9
9
25
0
0
9
0
9
9
0
% S
% Thr:
0
0
0
0
0
9
0
9
0
9
0
9
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
0
9
17
9
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _