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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
36.97
Human Site:
S374
Identified Species:
73.94
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S374
Q
G
Y
Q
L
I
G
S
H
S
G
V
K
L
C
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
F28
R
F
Y
I
Y
L
G
F
A
V
S
I
S
L
W
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S391
Q
G
Y
Q
L
I
G
S
H
S
G
V
K
L
C
Dog
Lupus familis
XP_536836
714
81505
S356
Q
G
Y
Q
L
I
G
S
H
S
G
V
K
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
S363
Q
G
Y
Q
L
I
G
S
H
S
G
V
K
L
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
S383
Q
G
Y
K
L
I
G
S
H
S
G
V
K
L
C
Frog
Xenopus laevis
Q2KHP8
735
84095
S377
Q
G
Y
R
L
I
G
S
H
S
G
V
K
L
C
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
S372
Q
G
Y
K
L
I
G
S
H
S
G
V
K
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
S355
Q
G
Y
R
I
I
G
S
H
S
G
V
K
L
C
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
T280
H
S
R
C
M
E
A
T
P
S
L
A
C
A
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
N334
T
P
S
L
A
C
A
N
K
C
V
F
C
W
R
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
S437
Q
G
Y
K
V
I
G
S
H
S
G
V
K
I
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
20
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
93.3
86.6
N.A.
N.A.
N.A.
N.A.
86.6
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
N.A.
100
100
93.3
N.A.
N.A.
N.A.
N.A.
100
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
80
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
17
0
9
0
0
9
0
9
0
% A
% Cys:
0
0
0
9
0
9
0
0
0
9
0
0
17
0
67
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
0
75
0
0
0
0
84
0
0
0
75
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
75
0
0
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
25
0
0
0
0
9
0
0
0
75
0
0
% K
% Leu:
0
0
0
9
59
9
0
0
0
0
9
0
0
75
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
75
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
9
17
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
0
9
9
0
0
0
0
75
0
84
9
0
9
0
0
% S
% Thr:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
9
9
75
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% W
% Tyr:
0
0
84
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _