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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
26.97
Human Site:
S386
Identified Species:
53.94
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S386
K
L
C
R
W
T
K
S
M
L
R
G
R
G
G
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
I40
S
L
W
I
C
V
Q
I
V
I
K
T
Q
G
K
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
V403
K
L
C
R
W
T
K
V
F
F
L
C
L
L
T
Dog
Lupus familis
XP_536836
714
81505
S368
K
L
C
R
W
T
K
S
M
L
R
G
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
S375
K
L
C
R
W
T
K
S
M
L
R
G
R
G
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
S395
K
L
C
R
W
T
K
S
M
L
R
G
R
G
G
Frog
Xenopus laevis
Q2KHP8
735
84095
S389
K
L
C
R
W
T
K
S
M
L
R
G
R
G
G
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
S384
K
L
R
R
W
T
K
S
M
L
R
G
R
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
S367
K
L
C
R
W
T
K
S
M
L
R
G
R
G
G
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
C292
C
A
N
K
C
V
F
C
W
R
H
H
T
N
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
P346
C
W
R
H
H
T
N
P
V
G
K
S
W
Q
W
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
N449
K
I
C
R
W
T
K
N
E
L
R
G
K
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
13.3
46.6
100
N.A.
100
N.A.
N.A.
N.A.
100
100
93.3
N.A.
N.A.
N.A.
N.A.
100
P-Site Similarity:
100
46.6
46.6
100
N.A.
100
N.A.
N.A.
N.A.
100
100
93.3
N.A.
N.A.
N.A.
N.A.
100
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
66.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
17
0
67
0
17
0
0
9
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
9
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
67
0
75
59
% G
% His:
0
0
0
9
9
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
9
0
9
0
0
0
0
0
% I
% Lys:
75
0
0
9
0
0
75
0
0
0
17
0
9
0
9
% K
% Leu:
0
75
0
0
0
0
0
0
0
67
9
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
9
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
0
% Q
% Arg:
0
0
17
75
0
0
0
0
0
9
67
0
59
0
0
% R
% Ser:
9
0
0
0
0
0
0
59
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
0
84
0
0
0
0
0
9
9
0
9
% T
% Val:
0
0
0
0
0
17
0
9
17
0
0
0
0
0
0
% V
% Trp:
0
9
9
0
75
0
0
0
9
0
0
0
9
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _