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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
12.42
Human Site:
S53
Identified Species:
24.85
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S53
G
K
N
L
Q
E
K
S
V
P
K
A
A
Q
D
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S70
D
R
S
L
Q
E
K
S
V
P
R
A
P
Q
D
Dog
Lupus familis
XP_536836
714
81505
S58
G
K
K
S
Q
E
K
S
V
P
K
A
T
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
G53
S
Q
E
K
R
V
P
G
A
P
D
S
S
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
V62
E
H
S
N
G
N
L
V
S
S
E
V
V
E
D
Frog
Xenopus laevis
Q2KHP8
735
84095
S57
N
E
T
V
C
N
G
S
L
L
L
K
T
K
A
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
V53
K
K
K
M
V
H
P
V
S
P
L
A
S
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
S56
F
S
R
Q
R
K
T
S
Q
Q
A
D
K
E
S
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
S38
L
K
H
L
K
N
L
S
L
N
P
S
S
T
L
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
P63
L
N
K
Q
Q
K
K
P
C
C
S
D
K
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
0
66.6
73.3
N.A.
6.6
N.A.
N.A.
N.A.
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
0
86.6
73.3
N.A.
33.3
N.A.
N.A.
N.A.
26.6
33.3
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
0
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
0
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
9
34
9
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
9
17
0
0
34
% D
% Glu:
9
9
9
0
0
25
0
0
0
0
9
0
0
17
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
9
0
9
9
0
0
0
0
0
9
0
% G
% His:
0
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
9
34
25
9
9
17
34
0
0
0
17
9
17
25
0
% K
% Leu:
17
0
0
25
0
0
17
0
17
9
17
0
0
9
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
9
9
0
25
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
9
0
42
9
0
9
0
0
% P
% Gln:
0
9
0
17
34
0
0
0
9
9
0
0
0
17
0
% Q
% Arg:
0
9
9
0
17
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
9
9
17
9
0
0
0
50
17
9
9
17
25
0
25
% S
% Thr:
0
0
9
0
0
0
9
0
0
0
0
0
17
9
0
% T
% Val:
0
0
0
9
9
9
0
17
25
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _